In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 141-86-6, name is 2,6-Diaminopyridine, the common compound, a new synthetic route is introduced below. Recommanded Product: 2,6-Diaminopyridine
Example 1 N, /V’-(pyridine-2, 6-diyl) dibenzamid 1) Synthetic Procedure: In a round bottom flask 2, 6-diaminopyridine (lg, 9.163 mmol) was dissolved in 40mL of dry dichloromethane and triethylamine (2.8mL, 27.72mmol) was added. Then, benzoyl chloride (2.5mL, 17.98 mmol) was added drop by drop and this mixture was stirred under inert atmosphere at room temperature for 15h. Reaction mixture was poured in water. Crude product was extracted in dichloromethane, organic layer was washed with water and dried over anhydrous sodium sulphate. The solvent was evaporated on rotary evaporator and crude product was purified by column chromatography on silica gel by eluting with ethyl acetate: hexane (40:60) mixture. The product was further purified by recrystallization using a methanol. Yield: 2.60 g (89%). NMR (200MHz, CDC13): delta ppm 7.54 (m, 6H), 7.90 (d, 4H, J=6Hz), 7.82 (t, 1H, J=8Hz), 8.10 (d, 2H, J=8Hz), 8.39 (s, 2H).
The synthetic route of 141-86-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; AMBADE, Ashootosh Vasant; PESALA, Bala; JOSHI, Kavita; BASUTKAR, Nitin Bapurao; RAY, Shaumik; DASH, Jyotirmayee; VILASRAO, Kaware Vaibhav; WO2015/104722; (2015); A1;,
Pyridine – Wikipedia,
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