Electric Literature of 198904-84-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 198904-84-6, name is tert-Butyl 2-(4-(pyridin-2-yl)benzylidene)hydrazinecarboxylate. This compound has unique chemical properties. The synthetic route is as follows.
1) Add 100kg of methanol to the 500L reactor,N1-(tert-butoxycarbonyl)-N2-[4-(2-pyridyl)benzylidene]hydrazine20 kg (molar amount 297.15,a molar amount of 67 mol), palladium with a palladium content of 0.5% is added to 2 kg, and the temperature is controlled at 35 C.After nitrogen replacement, hydrogenation was carried out, and the reaction was monitored by HPLC, and the reaction was completed in 12 hours;2) Reaction hydraulic filtration, the filtrate was concentrated to dryness under reduced pressure, and the weight of the liquid oil was 20 kg, and the mixture was beaten with n-hexane overnight, and dried to obtain 17.3 kg of solid, the yield was 86.6%, and the purity was 99.3%.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 198904-84-6, tert-Butyl 2-(4-(pyridin-2-yl)benzylidene)hydrazinecarboxylate.
Reference:
Patent; Changzhou Jien Pharmaceutical Co., Ltd.; Wang Yuqin; Zhong Chongchao; Xu Jing; (7 pag.)CN109574916; (2019); A;,
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