Sonavane, Sachin; Deshmukh, Ganesh; Wakchaure, Satish; Deshmukh, Sharayu published their research in Heterocyclic Letters in 2021. The article was titled 《An improved, practical, reliable and scalable synthesis of 2,5-dibromopyridine》.Product Details of 624-28-2 The article contains the following contents:
A convenient and scalable process for preparation of 2,5-dibromopyridine has been developed. Total yield of 83% has been achieved from 2-aminopyridine. The process is convenient and could be easily scaled up. Byproduct dibromide pyridine is separated and 2-amino-5-bromopyridine is converted by modified Sandmeyer conditions to synthesize 2,5-dibromopyridine from its diazonium salt in presence of bromine instead of conventional copper halide such as CuBr as reagents or catalysts. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dibromopyridine(cas: 624-28-2Product Details of 624-28-2)
2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Product Details of 624-28-2