Pyridine is colorless, but older or impure samples can appear yellow. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Electric Literature of 16133-25-8.
Song, Fan;Yang, Chao;Shao, Xiaotao;Du, Lei;Zhu, Jing;Kan, Chun research published 《 A reversible “turn-off-on” fluorescent probe for real-time visualization of mercury(II) in environmental samples and its biological applications》, the research content is summarized as follows. In this study, we synthesized a novel fluorescent probe (S-TC) based on Thiooxo-Rhodamine B. In the design of the probe, we sulfided carbonyl groups of rhodamine spironolactam to thiocarbonyl groups. C=S functional group was used as a recognition group for Hg2+. S-TC has a good spectral response to Hg2+ in the EtOH/H2O solution (1:1, volume/volume) with low detection limits and high binding constants The detection limit and the association constant was calculated as 0.077 μM and 1.70 × 104 M-1, resp. S-TC displayed the traditional reversible “turn-off-on” fluorescence change with 1:1 binding stoichiometry. It is feasible to detect Hg2+ in real environmental water by S-TC. Biol. experiments demonstrated that S-TC can be used to detect to Hg2+ in living cells, animals and plant tissues.
16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Electric Literature of 16133-25-8