Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Formula: C5H4ClNO2S.
Song, Qinghao;Zhao, He;Sun, Yanping;Jiang, Huanfeng;Zhang, Min research published 《 Direct C(sp3)-H Sulfonylation of Xanthene Derivatives with Sodium Sulfinates by Oxidative Copper Catalysis》, the research content is summarized as follows. By employing a readily available CuCl/DDQ catalyst system, herein a direct C(sp3)-H sulfonylation of xanthene derivates I (R = H, Me; R1 = H, Me, Cl, Et, etc.;RR1 = -CH=CH-CH=CH-; R2 = H, Me, Br, CF3, Ph; R3 = H, Me, Et, Cl; Z = O, S, NCH3, NBn, etc.) with odorless sodium sulfinates R4S(O)2Na (R4 = Me, Ph, 4-chlorophenyl, thiophen-2-yl, etc.) was reported. Various 9H-xanthenes I (Z = O), thioxanthenes I (Z = S), and 9,10-dihydroacridines I (Z = NCH3, NPh, NBn, NCbz) are efficiently transformed into the desired benzylic sulfonyl products II via a radical/radical cross-coupling process, proceeding with the merits of broad substrate scope, operational simplicity, good functional group compatibility, and mild reaction conditions.
Formula: C5H4ClNO2S, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.