Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. COA of Formula: C6H4BrNO.
Song, Xiaoxiao;Fan, Yanjun;Zhu, Zhiming;Ni, Qijian research published 《 Chiral Phosphoric Acid-Catalyzed Asymmetric Arylation of Indolizines: Atroposelective Access to Axially Chiral 3-Arylindolizines》, the research content is summarized as follows. A highly straightforward strategy for the synthesis of a new axially chiral 3-arylindolizine I (R = Me, Bn, n-Pr, etc.; R1 = H, 5-Me, 6-Cl, 8-F, etc.; R2 = 2-nitrophenyl, ethoxycarbonyl, (benzyloxy)carbonyl, etc.) and Et 3-[3,6-dihydroxy-2-(methoxycarbonyl)phenyl]indolizine-2-carboxylate scaffold via organocatalytic asym. arylation reactions of indolizinecarboxylates and p-quinone esters and Me 3,6-dioxocyclohexa-1,4-diene-1-carboxylate was reported. Using the chiral phosphoric acid catalyst, a series of axially chiral 3-arylindolizines I was accessed in good to excellent yields and atropo-enantioselectivities. This approach features a broad substrate scope, mild reaction conditions, good scalability, and facile derivatization. Moreover, preliminary investigations based on nonlinear effects and a thermal racemization study demonstrated the intrinsic pathway for the formation of axial chirality and its potential utility.
31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.
5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., COA of Formula: C6H4BrNO