100-55-0, Adding a certain compound to certain chemical reactions, such as: 100-55-0, 3-Pyridinemethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 100-55-0, blongs to pyridine-derivatives compound.
General procedure: In a 10 ml screw-capped vial was placed 2 mol% of manganese (I) catalyst, 1 equivalent of thebase, 0.1 ml of toluene , 0.2 mmol of alcohol and 0.4 mmol of amine under argon atmosphere. The reaction mixture was heated at 140C for 24 h in an oil bath. The reaction mixture was then cooledat ambient temperature, quenched with water and the organic layer was extracted with ethylacetate. The combined organic layers were dried over sodium sulfate and concentrated. 1H NMR yields were determined using 1,3,5-trimethoxy benzene as an internal standard. The product waspurified by silica gel column chromatography using the mixture of ethyl acetate and hexane aseluent.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,100-55-0, its application will become more common.
Reference:
Article; Das, Kuhali; Kumar, Amol; Jana, Akash; Maji, Biplab; Inorganica Chimica Acta; vol. 502; (2020);,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem