Related Products of 1050501-88-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1050501-88-6, name is 2-Bromo-6-chloropyridin-3-amine. This compound has unique chemical properties. The synthetic route is as follows.
Step 2: synthesis of 5-chloro-1H-pyrrolo[3,2-bjpyridine-2-carboxylic acid (intermediate 20b)2-oxopropanoic acid (36.22 g, 411.31 mmol), palladium(II)acetate (7.74 g, 34.15 mmol) and Et3N (69.11 g, 682.94 mmol) were added to a solution of 2-bromo-6- chloropyridin-3-amine 20a (32.20 g, 155.21 mmol) and TPP (35.83 g, 136.59 mmol) in dry DMF (300 ml). The reaction mixture was stirred at 100C overnight. The solvent was then evaporated, water was added and the water layer was washed with EtOAc.The water layer was acidified with conc. HC1. The precipitate was filtered off and dried, yielding 25.21 g of the wanted product 20b (82.6 %). m/z = 197.1 (M+H), Cl pattern.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1050501-88-6, 2-Bromo-6-chloropyridin-3-amine.
Reference:
Patent; JANSSEN R&D IRELAND; TAHRI, Abdellah; VENDEVILLE, Sandrine Marie Helene; JONCKERS, Tim Hugo Maria; RABOISSON, Pierre Jean-Marie Bernard; HU, Lili; DEMIN, Samuel Dominique; COOYMANS, Ludwig Paul; WO2014/60411; (2014); A1;,
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