1121-60-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1121-60-4, name is Picolinaldehyde, molecular formula is C6H5NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
2-(1H-Imidazol-2-yl)-pyridine A round bottom flask was charged with 2-pyridinecarboxaldehyde (5.0 g), glyoxal (10.7 mL, 40% in water), and methanol (100 mL). This mixture was stirred at room temp as 26 mL of concentrated aqueous ammonia was added portion-wise. After 1 h, the solvents were removed, and the remaining brown residue was recrystallized in acetonitrile (ca. 40 mL). The product 2-(1H-Imidazol-2-yl)-pyridine was collected as brown crystals.
The chemical industry reduces the impact on the environment during synthesis 1121-60-4, I believe this compound will play a more active role in future production and life.
Reference:
Patent; Leivers, Martin Robert; Lauchli, Ryan; US2010/29655; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem