Related Products of 1187830-47-2, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1187830-47-2, name is 4,5,6,7-Tetrahydro-2H-pyrazolo[4,3-b]pyridine hydrochloride, molecular formula is C6H10ClN3, molecular weight is 159.62, as common compound, the synthetic route is as follows.
a) 4,5,6,7-Tetrahydro-2H-pyrazolo[4,3-b]pyridine.HCl (319 mg, 2 mmol) was combined with Boc2O (480 mg, 2.2 mmol) and K2CO3 (1.3 mL, 3 M aqueous, 2 equiv) in CH2Cl2 (10 mL). After 15 hours, the starting amine was consumed (LCMS). The reaction slurry was washed with brine and the organic layer was dried on MgSO4, filtered, and concentrated to give a viscous yellow oil (446 mg, 96%) that was used without further purification. MS: (ES) m/z calculated for C11H18N3O2 [M+H]+ 224.1, found 224.2.
Statistics shows that 1187830-47-2 is playing an increasingly important role. we look forward to future research findings about 4,5,6,7-Tetrahydro-2H-pyrazolo[4,3-b]pyridine hydrochloride.
Reference:
Patent; ChemoCentryx, Inc.; Chen, Xi; Dragoli, Dean R.; Fan, Pingchen; Li, Yandong; Powers, Jay P.; Punna, Sreenivas; Tanaka, Hiroko; Zhang, Penglie; US2014/57937; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem