Related Products of 153034-88-9, Adding some certain compound to certain chemical reactions, such as: 153034-88-9, name is 2-Chloro-4-iodo-3-methylpyridine,molecular formula is C6H5ClIN, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 153034-88-9.
A mixture of 2-chloro-4-iodo-3-methylpyridine (250 mg, 986 mumol) (AstaTech, catNo.22441) and boric acid, trimethyl ester (224 muL, 1.97 mmol) in tetrahydrofuran (5.0 mL) was added 2.5 M n-butyllithium in hexanes (789 muL, 1.97 mmol) dropwise at -78 C. The reaction mixture was allowed to warm up to r.t. after 90 min and stirred for another 30 min. The resulting mixture was concentrated and acetonitrile (5 mL) was added. The resulting suspension was filtered through celite then concentrated to give the desired product. LCMS calculated for C6H8BClNO2 (M+H)+: m/z=172.2; found 172.2
According to the analysis of related databases, 153034-88-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Incyte Corporation; Li, Zhenwu; Wu, Liangxing; Yao, Wenqing; (48 pag.)US2017/320875; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem