The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 39856-58-1, name is 2-Bromopyridin-3-amine. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 2-Bromopyridin-3-amine
1.22 ml 2-oxo-propionic acid, 0.26 g palladium acetate and 3.20 ml triethylamine were added to a solution of 1.00 g 2-bromo-pyridin-3-yl amine and 1.21 g triphenyl-phosphine in 10 ml N,N-dimethylformamide. The reaction mixture was stirred for 4 hours at 100C. After removal of the solvent under reduced pressure, the residue was purified by column chromatography on silica gel with dichloromethane/ methanol as eluent. Yield: 260 mg MS(ES+): m/e=163. 1H-NMR (400 MHz, DMSO/TMS): delta = 13.30 (s, 1H); 12.00 (s, 1H); 8.45 (d, 1H); 7.82 (d, 1H); 7.25 (dd, 1H); 7.14 (s, 1H)
With the rapid development of chemical substances, we look forward to future research findings about 39856-58-1.
Reference:
Patent; Aventis Pharma Deutschland GmbH; EP1479680; (2004); A1;,
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