Adding a certain compound to certain chemical reactions, such as: 6443-85-2, 2-(Pyridin-3-yl)acetonitrile, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 6443-85-2, blongs to pyridine-derivatives compound. Quality Control of 2-(Pyridin-3-yl)acetonitrile
b) 2-(3-pyridyl)ethylamine dihydrochloride was prepared as follows. A mixture of 1.3 g 3-pyridylacetonitrile, approximately 3 g Raney nickel and 30 ml methanol containing 10% ammonia by volume was hydrogenated at 35 psi for 20 hr using a Parr hydrogenator. The catalyst was filtered off over celite and the filtrate was evaporated. The residue was dissolved in methylene chloride, dried with magnesium sulfate, filtered and evaporated. The product was converted to the dihydrochloride using hydrogen chloride in dioxane. Crystallization from methanol/ether gave 1.4 g colorless crystals having a mp 145-148 C.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,6443-85-2, its application will become more common.
Reference:
Patent; Aventis Pharmaceuticals Inc.; US6759384; (2004); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem