Synthetic Route of 524955-09-7, Adding some certain compound to certain chemical reactions, such as: 524955-09-7, name is 3-Chloro-4-(pyridin-2-ylmethoxy)aniline,molecular formula is C12H11ClN2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 524955-09-7.
General procedure: A mixture of (E)-N’-(2-cyano-4-nitrophenyl)-N,N-dimethylformimidamide (5) (2.99g, 13.7 mmol) and appropriate aniline (15.1 mmol) in glacial acetic acid (15.0mL) was refluxed for 2 h. The acetic acid was evaporated and the solid waswashed with water and diethyl ether and dried to afford the titled compounds.
According to the analysis of related databases, 524955-09-7, the application of this compound in the production field has become more and more popular.
Reference:
Article; Elkamhawy, Ahmed; Farag, Ahmed Karam; Viswanath, Ambily Nath Indu; Bedair, Tarek M.; Leem, Dong Gyu; Lee, Kyung-Tae; Pae, Ae Nim; Roh, Eun Joo; Bioorganic and Medicinal Chemistry Letters; vol. 25; 22; (2015); p. 5147 – 5154;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem