Sources of common compounds: 4-Ethoxy-3-nitropyridine

According to the analysis of related databases, 1796-84-5, the application of this compound in the production field has become more and more popular.

Reference of 1796-84-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1796-84-5, name is 4-Ethoxy-3-nitropyridine. This compound has unique chemical properties. The synthetic route is as follows.

Step 4: 1-N,N-Dimethylcarbamoyl-4-methoxycarbonyl-3-[5-(N-3-nitropyridin-4-yl)aminomethylthien-2-oyl]indole. To a solution of 1-N,N-dimethylcarbamoyl4-methoxycarbonyl-3-(5-aminomethylthien-2-oyl)indole (0.896 g, 2.33 mmol) in CH3 CN (5 mL) was added 4-ethoxy-3-nitropyridine (0.428 g, 2.55 mmol) and the reaction mixture was heated at reflux for 17 hours, then the solvent was removed in vacuo and the residue heated at 100 C. for 2 hours. The reaction mixture was then put under high vacuum to give 1-N,N-dimethylcarbamoyl-4-methoxycarbonyl-3-[5-(N-3-nitropyridin-4-yl)aminomethylthien-2-oyl]indole as a brown foam which was used without further purification.

According to the analysis of related databases, 1796-84-5, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Abbott Laboratories; US5486525; (1996); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem