Application of 845826-99-5, Adding some certain compound to certain chemical reactions, such as: 845826-99-5, name is 5-(4-Fluorophenyl)picolinic acid,molecular formula is C12H8FNO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 845826-99-5.
General procedure: Oxalyl chloride (0.5mmol) was added drop-wise to a stirred mixture of compounds 4a-k or 5a-k (0.2mmol) and DMF (0.01mmol) in dichloromethane (10mL) in room temperature for 10min, and the mixture was distilled and dissolved in dichloromethane (10mL) immediately. The solution was used for the next step without further purification.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 845826-99-5, 5-(4-Fluorophenyl)picolinic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Zhu, Wufu; Wang, Wenhui; Xu, Shan; Tang, Qidong; Luo, Rong; Wang, Min; Gong, Ping; Zheng, Pengwu; Bioorganic and Medicinal Chemistry; vol. 24; 4; (2016); p. 812 – 819;,
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