Sources of common compounds: 5-Bromo-3-methyl-1H-pyrazolo[3,4-c]pyridine

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 929617-30-1, 5-Bromo-3-methyl-1H-pyrazolo[3,4-c]pyridine, other downstream synthetic routes, hurry up and to see.

Application of 929617-30-1, Adding some certain compound to certain chemical reactions, such as: 929617-30-1, name is 5-Bromo-3-methyl-1H-pyrazolo[3,4-c]pyridine,molecular formula is C7H6BrN3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 929617-30-1.

To a solution of 5-Bromo-3-methyl-lH-pyrazolo[3,4-c]pyridine from Example 102 (106 mg, 0.5 mmol) in DMF (5 mL) was added Pd(dppf)Cl2 ( 20 mg ), saturated solution of Na2C03 ( 1 mL ) and lH-pyrazol-3-ylboronic acid ( 67 mg, 0.6 mmol ). The mixture was stirred under argon for 16 h at 80 C. After cooling down, the solvent was removed under reduced pressure and the residue was purified by silica-gel column chromatography (mobile phase: EA:PE = 1 : 1) to afford 103 (15 mg, 15% ). 1H NMR (500 MHz, MeOD) delta 8.96 (s, 1H), 8.23 (s, 1H), 7.71 (s, 1H), 6.90 (d, J= 1.5, 1H), 2.65 (s, 3H). ESI MS m/z = 200.1 (M+l)

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 929617-30-1, 5-Bromo-3-methyl-1H-pyrazolo[3,4-c]pyridine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; DO, Steven; HU, Huiyong; KOLESNIKOV, Aleksandr; LEE, Wendy; TSUI, Vickie Hsiao-Wei; WANG, Xiaojing; WEN, Zhaoyang; WO2013/24002; (2013); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem