Sources of common compounds: 5-Chloro-2-methyl-3-pyridinecarboxylic acid

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1092286-30-0, 5-Chloro-2-methyl-3-pyridinecarboxylic acid, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 1092286-30-0, 5-Chloro-2-methyl-3-pyridinecarboxylic acid, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 1092286-30-0, blongs to pyridine-derivatives compound. Recommanded Product: 1092286-30-0

5-Chloro-2-methylnicotinoyl chloride5-Chloro-2-methyl-nicotinic acid (4.15 g, 24.2 mmol) was placed in a flask with DCM (100 ml) and oxalyl chloride (3.68 g, 29 mmol). DMF (200muIota) was added and the reaction mixture was stirred at RT for 1 hour (gas evolution). The mixture was filtered and the solvent was removed in vacuo to afford the title product which was used without further purification.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1092286-30-0, 5-Chloro-2-methyl-3-pyridinecarboxylic acid, and friends who are interested can also refer to it.

Reference:
Patent; NOVARTIS AG; BEATTIE, David; BRUCE, Ian; COLSON, Anny-Odile; CULSHAW, Andrew James; SHARP, Thomas; WO2011/95450; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem