Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 6318-51-0, name is (4-Chlorophenyl)(pyridin-2-yl)methanone. A new synthetic method of this compound is introduced below., Quality Control of (4-Chlorophenyl)(pyridin-2-yl)methanone
General procedure: Bioconversion was conducted with 20 mM 1a-10a,20 U·mL-1KpADH variants, 40 mM isopropanol in PBS buffer (pH 7.0,100 mM) in total volume of 2 mL at 30 C and 180 rpm overnight. Then,1 mL of the reaction mixture was withdrawn and extracted with ethylacetate. The organic phase was isolated by centrifugation and driedover anhydrous MgSO4. The conversion rate and enantioselectivity ofthe products were analyzed as described in supporting information.
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Reference:
Article; Wang, Yue; Dai, Wei; Liu, Yongmei; Zhang, Zhongwei; Zhou, Jieyu; Xu, Guochao; Ni, Ye; Catalysis Communications; vol. 108; (2018); p. 1 – 6;,
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