Related Products of 754131-60-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 754131-60-7, name is 3-Bromo-2-(bromomethyl)pyridine. This compound has unique chemical properties. The synthetic route is as follows.
To a stirred solution of the above crude 3-bromo-2-bromomethylpyridine (70g, 0. 28MOL) in dioxane (SOOML) and water (250mL), was added NACN (28g, 0. 74MOL) at 0C and then stirred at RT for 16h. The reaction mixture was quenched with 3Lit of water and extracted with ethylacetate (4X500ML). The organic layer was washed with water (400L), brine (250mL), dried over NA2SO4 and concentrated to give crude product. The crude was purified by column chromatography over silica gel (pet. ether/ethylacetate, 8: 2) to give 3- BROMOPYRIDINE-2-YL-ACETONITRILE (22g, 40%). [TLC: Pet. ether/ethylacetate, 7: 3, RF= 0. 35] MS (EST) : 199.2 ; MS (ESR) : 197.2.
According to the analysis of related databases, 754131-60-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; APPLIED RESEARCH SYSTEMS ARS HOLDING N. V.; WO2004/98607; (2004); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem