Application of 24484-93-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 24484-93-3, name is Methyl 4-chloropicolinate. This compound has unique chemical properties. The synthetic route is as follows.
4-Chloro-2-picolinic acid methyl ester(10 g, 58.3 mmol) was added to 70 mL of methanol and stirred to dissolve,Cooled to 0-5 C with stirring,Then, methylamine (5.4 g, 0.175 mol) in methanol (40 mL) was added dropwise with constant stirring,The dropping process temperature is maintained at 0-5 C.Drop finished,Reaction at 0-5 C for 4 h.The solvent is recovered under reduced pressure,The residue was added to 200 mL of ethyl acetate,Stir evenly after filtration,The filtrate was washed with saturated brine,Dried over anhydrous sodium sulfate,Concentrated under reduced pressure,crystallization,filter,washing,dry,To give 9.4 g of pale yellow crystals,Yield 94.5%
According to the analysis of related databases, 24484-93-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Yantai University; Yao Jianwen; Kong Xiangkai; Chen Jing; Wang Chengpeng; Zhang Guoying; (26 pag.)CN104045598; (2017); B;,
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