Sources of common compounds: N-Hydroxynicotinimidamide

According to the analysis of related databases, 1594-58-7, the application of this compound in the production field has become more and more popular.

Synthetic Route of 1594-58-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1594-58-7, name is N-Hydroxynicotinimidamide. This compound has unique chemical properties. The synthetic route is as follows.

EXAMPLE 15 4.7 g (5.5 ml; 55 mmol) of piperidine are added over 20 minutes to the solution of 5.1 g (4.3 ml; 55 mmol) of epichlorohydrin in 5.2 ml of tert-butanol under cooling by water while stirring vigorously. The reaction mixture is stirred at room temperature for 1 hour, then 50 ml of pure dry DMF, 6.9 g (50 mmol) of nicotinic acid amidoxime and 3.2 g (80 mmol) of powdered sodium hydroxide are added. After stirring the suspension at 70 C. for 12 hours the reaction mixture is worked up as described in Example 1 to give 13.2 g (75%) of O(3-amino-2-hydroxypropyl) nicotinic acid amidoxime dihydrochloride.

According to the analysis of related databases, 1594-58-7, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Chinoin Gyogyszar es Vegyeszeti Termekek Gyara Rt.; US5239077; (1993); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem