In 2022,Su, Fangyao; Zhao, Qianrui; Wang, Mengzhuo; Zhao, Mingzhang; Ren, Yihe; Zhu, Binghan; Chen, Haoran; Lai, Miao; Zhao, Mingqin published an article in ChemistrySelect. The title of the article was 《A Convenient Esterification of N-Heteroarene Methanols via C-CN Bond Cleavage of Benzoyl Cyanides as Acylating Sources》.Formula: C7H9NO The author mentioned the following in the article:
An efficient and straightforward methodol. for the esterification of various N-heteroarene methanols using benzoyl cyanides as acylating sources through a simply mixing conditions has been reported. The acyl groups were in-situ generated via chemoselective C-CN bond cleavage to give the N-heteroarenemethyl esters. This process features in readily accessible starting materials and offers an easy operational procedure, and broad substrate scope with excellent selectivity. In the experiment, the researchers used many compounds, for example, 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Formula: C7H9NO)
2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Formula: C7H9NO