Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Name: 5-Bromo-2-fluoropyridine.
Sun, Deli;Ma, Guobin;Zhao, Xinluo;Lei, Chuanhu;Gong, Hegui research published 《 Nickel-catalyzed asymmetric reductive arylation of α-chlorosulfones with aryl halides》, the research content is summarized as follows. An asym. Ni-catalyzed reductive cross-coupling of aryl/heteroaryl halides with racemic α-chlorosulfones to afford enantioenriched sulfones I [R1 = Me, Ph, 2-thienyl, etc.; R2 = Me, n-Bu, Bn, etc.; Ar = 4-MeOOCC6H4, 2-methoxy-pyridin-5-yl, 2-naphthyl, etc.] was reported. The reaction tolerated a variety of functional groups under mild reaction conditions, which complements current methods. The utility of this work was demonstrated by facile late-stage functionalization of com. drugs.
Name: 5-Bromo-2-fluoropyridine, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , 766-11-0.