At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. COA of Formula: C5H4ClNO2S.
Sun, Yucong;Feng, Cancan;Wang, Peisong;Yang, Fan;Wu, Yangjie research published 《 Cobalt-catalyzed C8-H sulfonylation of 1-naphthylamine derivatives with sodium sulfinates》, the research content is summarized as follows. A facile and efficient protocol for cobalt-catalyzed regioselective C8-H sulfonylation of 1-naphthylamine derivatives with sodium sulfinates, affording sulfonylated naphthylamines in moderate to good yields was described. The reaction exhibited broad functional group tolerance and high regioselectivity. Note that the addition of a catalytic amount of NFSI or Selectfluor as the auxiliary ligand would enhance the reaction efficiency. Furthermore, the picolinamide moiety as a bidentate directing group likely played a key role in this regioselective transformation.
COA of Formula: C5H4ClNO2S, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.