Gold-Catalyzed Direct Alkynylation of Azulenes was written by Szekely, Anna;Peter, Aron;Aradi, Klara;Tolnai, Gergely L.;Novak, Zoltan. And the article was included in Organic Letters in 2017.Formula: C10H16BrN This article mentions the following:
A novel catalytic method for the direct C-H alkynylation of azulenes is developed. The gold catalyzed functionalization of this special carbacycle is achieved with hypervalent iodonium reagent TIPS-EBX under mild reaction conditions. With the aid of the developed procedure, several TIPS alkynylated azulene derivatives, e.g., I, were synthesized bearing important functional groups for further functionalization. In the experiment, the researchers used many compounds, for example, 1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6Formula: C10H16BrN).
1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Formula: C10H16BrN