Tag: 0-100

Xie, Jinfeng et al. published their research in Waste and Biomass Valorization in 2020 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Electric Literature of C5H5NO

Metalloporphyrin as a Biomimetic Catalyst for the Catalytic Oxidative Degradation of Lignin to Produce Aromatic Monomers was written by Xie, Jinfeng;Ma, Guanfeng;Ouyang, Xinping;Zhao, Lisha;Qiu, Xueqing. And the article was included in Waste and Biomass Valorization in 2020.Electric Literature of C5H5NO This article mentions the following:

Lignin, an abundant biomass waste, was degraded under microwave irradiation with H2O2 as the oxidant and metalloporphyrin as the catalyst. The effect of substituent group (4-methylphenyl, 4-methoxyphenyl, 4-bromophenyl and 4-carboxyphenyl) at the meso-benzene ring of metalloporphyrin, central metal ion (Co, Mn, Ni and Fe) and axial ligand (chlorine, p-hydroxypyridine, p-pyridinecarboxaldehyde) on the degradation of lignin was investigated. The electron-withdrawing group not only reduces the electron cloud d. on the porphyrin ring, but also promotes the formation of higher active intermediate [(Porp)MeIV=O]+·. Therefore, the presence of stronger electron-withdrawing substituents makes the metalloporphyrins more efficient in lignin degradation Compared to Co porphyrin, there are less amount of [(Porp)MeIV=O]+· formed when Mn, Fe or Ni porphyrin was used as the catalyst for degrading lignin. Consequently, Co porphyrin contributed to a higher YAM (the yield of aromatic monomers). The strong nucleophilicity and the low steric hindrance of axial ligand was advantageous for the stability of metalloporphyrins, which is favorable for improving the catalytic activity to the degradation of lignin. It is found that the YAM increases 20.1% from 5.6% by using CoTBrPPCl as the reaction catalyst under the optimized conditions. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Electric Literature of C5H5NO).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Electric Literature of C5H5NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xie, Jinfeng et al. published their research in Waste and Biomass Valorization in 2020 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Electric Literature of C5H5NO

Metalloporphyrin as a Biomimetic Catalyst for the Catalytic Oxidative Degradation of Lignin to Produce Aromatic Monomers was written by Xie, Jinfeng;Ma, Guanfeng;Ouyang, Xinping;Zhao, Lisha;Qiu, Xueqing. And the article was included in Waste and Biomass Valorization in 2020.Electric Literature of C5H5NO This article mentions the following:

Lignin, an abundant biomass waste, was degraded under microwave irradiation with H2O2 as the oxidant and metalloporphyrin as the catalyst. The effect of substituent group (4-methylphenyl, 4-methoxyphenyl, 4-bromophenyl and 4-carboxyphenyl) at the meso-benzene ring of metalloporphyrin, central metal ion (Co, Mn, Ni and Fe) and axial ligand (chlorine, p-hydroxypyridine, p-pyridinecarboxaldehyde) on the degradation of lignin was investigated. The electron-withdrawing group not only reduces the electron cloud d. on the porphyrin ring, but also promotes the formation of higher active intermediate [(Porp)MeIV=O]+·. Therefore, the presence of stronger electron-withdrawing substituents makes the metalloporphyrins more efficient in lignin degradation Compared to Co porphyrin, there are less amount of [(Porp)MeIV=O]+· formed when Mn, Fe or Ni porphyrin was used as the catalyst for degrading lignin. Consequently, Co porphyrin contributed to a higher YAM (the yield of aromatic monomers). The strong nucleophilicity and the low steric hindrance of axial ligand was advantageous for the stability of metalloporphyrins, which is favorable for improving the catalytic activity to the degradation of lignin. It is found that the YAM increases 20.1% from 5.6% by using CoTBrPPCl as the reaction catalyst under the optimized conditions. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Electric Literature of C5H5NO).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Electric Literature of C5H5NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pesci, Rafaela B. P. et al. published their research in Journal of Molecular Structure in 2019 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.COA of Formula: C5H5NO

Supramolecular structures in oxovanadium(IV) compounds with pyrid-2-one and pyrid-4-one ligands was written by Pesci, Rafaela B. P.;de Souza, Eliseu J.;Niquet, Elke;Nascimento, Otaciro R.;Viana, Rommel B.;Deflon, Victor M.. And the article was included in Journal of Molecular Structure in 2019.COA of Formula: C5H5NO This article mentions the following:

The aim of this study is to perform an anal. of the spectroscopic and electronic properties of three vanadium(IV) complexes formed from bis(acetylacetonato)oxovanadium(IV) [VO(acac)2] and pyrid-2-one (2pyon) or pyrid-4-one (4pyon) ligands: [VO(acac)2(2pyon)] (1), [VO(acac)2(4pyon)] (2) and [VO(acac)2(H2O)]·4pyon (3). In 1 and 2, the pyridone ligand coordinates neutral and monodentate to the vanadium center, with the oxygen atom placed in the axial trans position to the oxo ligand. In 3, the 4pyon ligand remains outside the metal 1st coordination sphere but bound to the aqua ligand through hydrogen bonds that gave a supramol. structure. Also, the D. Functional Theory (DFT) were applied to answer two overarching aspects. First, in complexes 1 and 2, the DFT anal. was used to establish the most stable configuration among the vanadium pyridone complex isomers, comparing the ligand via O-bound pyridone and N-bound hydroxypyridine chelating modes. Second, DFT was also performed to enable understanding of the intermol. interactions between the 4pyon and the [VO(acac)2(H2O)] moiety to elucidate the intermol. interactions in 3. Further insights were also obtained by applying the Natural Bond Orbital anal. (NBO) along with a topol. perspective via the use of the Quantum Theory of Atoms in Mols. (QTAIM). In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2COA of Formula: C5H5NO).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.COA of Formula: C5H5NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Al-Sanea, M. M. et al. published their research in Russian Journal of Organic Chemistry in 2020 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of Pyridin-4-ol

Design, Synthesis and In Vitro Cytotoxic Activity of Certain 2-[3-Phenyl-4-(pyrimidin-4-yl)-1H-pyrazol1-yl]acetamide Derivatives was written by Al-Sanea, M. M.;Parambi, D. G. T.;Shaker, M. E.;Elsherif, H. A. M.;Elshemy, H. A. H.;Bakr, R. B.;Al-Warhi, T. I. M.;Gamal, M.;Abdelgawad, M. A.. And the article was included in Russian Journal of Organic Chemistry in 2020.Application In Synthesis of Pyridin-4-ol This article mentions the following:

A series of 2-[4-(2-oxypyrimidin-4-yl)-3-(3-methoxy-5-methylphenyl)-1H-pyrazol-1-yl]acetamide derivatives I [Ar = pyridin-3-yl, 2-H2NC6H4, 4-MeOC6H4, etc.] was synthesized and their in vitro antiproliferative activity was assessed against 60 NCI cell lines at a single dose concentration of 10μM. Compound I [Ar = 3,4-(MeO)2C6H3] showed an appreciable cancer cell growth inhibition (about 20%) against eight cancer cell lines (HOP-92, NCI-H226, 79SNB-75, A498, SN12C, UO-31, T-47D and MDA-MB-468). In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application In Synthesis of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cui, Guokai et al. published their research in Fuel in 2021 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Reference of 626-64-2

Tuning the structure of pyridinolate-based functional ionic liquids for highly efficient SO2 absorption was written by Cui, Guokai;Lyu, Shuzhen;Wang, Huiyong;Li, Zhiyong;Zhang, Ruina;Wang, Jianji. And the article was included in Fuel in 2021.Reference of 626-64-2 This article mentions the following:

A series of pyridinolate anion-functional ionic liquids (ILs) containing different kinds of cations were designed and prepared, including tri-n-hexyltetradecylphosphonium [P66614], tri-n-butylethylphosphonium [P4442], and 1,1,3,3-tetramethylguandinium [TMG] cations and pyridinolate [PyO] anions with different N positions. Densities and viscosities at different temperatures were measured because of their importance for the absorption of SO2. Effect of different structures on the absorption of SO2 was studied, including the type and the alkyl chain length of cations, and the N positions of [PyO] anions (2-, 3-, and 4-). Addnl., effects of SO2 concentration and temperature for absorption were investigated. Especially, up to 6.00 and 2.53 mol SO2 per mol IL could be obtained by [P66614][4-PyO] at 1 bar and 0.1 bar of SO2, resp., when absorptions performed at 20°C. The results indicate that (1) the aprotic cations weakened the cation···anion interaction and resulted in the released active sites on the anions, and (2) N position has an influence on charge distribution of [PyO] anions and resulted in the tunable absorption of SO2. Reversible SO2 absorption and [P66614][4-PyO] regeneration could be performed several times without losing efficiency. Furthermore, the mechanism of absorption was studied through FT-IR and NMR methods and the results showed that the absorption of SO2 by [P66614][4-PyO] includes physisorption and chemisorption. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Reference of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Reference of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pesci, Rafaela B. P. et al. published their research in Journal of Molecular Structure in 2019 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.COA of Formula: C5H5NO

Supramolecular structures in oxovanadium(IV) compounds with pyrid-2-one and pyrid-4-one ligands was written by Pesci, Rafaela B. P.;de Souza, Eliseu J.;Niquet, Elke;Nascimento, Otaciro R.;Viana, Rommel B.;Deflon, Victor M.. And the article was included in Journal of Molecular Structure in 2019.COA of Formula: C5H5NO This article mentions the following:

The aim of this study is to perform an anal. of the spectroscopic and electronic properties of three vanadium(IV) complexes formed from bis(acetylacetonato)oxovanadium(IV) [VO(acac)2] and pyrid-2-one (2pyon) or pyrid-4-one (4pyon) ligands: [VO(acac)2(2pyon)] (1), [VO(acac)2(4pyon)] (2) and [VO(acac)2(H2O)]·4pyon (3). In 1 and 2, the pyridone ligand coordinates neutral and monodentate to the vanadium center, with the oxygen atom placed in the axial trans position to the oxo ligand. In 3, the 4pyon ligand remains outside the metal 1st coordination sphere but bound to the aqua ligand through hydrogen bonds that gave a supramol. structure. Also, the D. Functional Theory (DFT) were applied to answer two overarching aspects. First, in complexes 1 and 2, the DFT anal. was used to establish the most stable configuration among the vanadium pyridone complex isomers, comparing the ligand via O-bound pyridone and N-bound hydroxypyridine chelating modes. Second, DFT was also performed to enable understanding of the intermol. interactions between the 4pyon and the [VO(acac)2(H2O)] moiety to elucidate the intermol. interactions in 3. Further insights were also obtained by applying the Natural Bond Orbital anal. (NBO) along with a topol. perspective via the use of the Quantum Theory of Atoms in Mols. (QTAIM). In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2COA of Formula: C5H5NO).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.COA of Formula: C5H5NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Al-Sanea, M. M. et al. published their research in Russian Journal of Organic Chemistry in 2020 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of Pyridin-4-ol

Design, Synthesis and In Vitro Cytotoxic Activity of Certain 2-[3-Phenyl-4-(pyrimidin-4-yl)-1H-pyrazol1-yl]acetamide Derivatives was written by Al-Sanea, M. M.;Parambi, D. G. T.;Shaker, M. E.;Elsherif, H. A. M.;Elshemy, H. A. H.;Bakr, R. B.;Al-Warhi, T. I. M.;Gamal, M.;Abdelgawad, M. A.. And the article was included in Russian Journal of Organic Chemistry in 2020.Application In Synthesis of Pyridin-4-ol This article mentions the following:

A series of 2-[4-(2-oxypyrimidin-4-yl)-3-(3-methoxy-5-methylphenyl)-1H-pyrazol-1-yl]acetamide derivatives I [Ar = pyridin-3-yl, 2-H2NC6H4, 4-MeOC6H4, etc.] was synthesized and their in vitro antiproliferative activity was assessed against 60 NCI cell lines at a single dose concentration of 10μM. Compound I [Ar = 3,4-(MeO)2C6H3] showed an appreciable cancer cell growth inhibition (about 20%) against eight cancer cell lines (HOP-92, NCI-H226, 79SNB-75, A498, SN12C, UO-31, T-47D and MDA-MB-468). In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application In Synthesis of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cui, Guokai et al. published their research in Fuel in 2021 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Reference of 626-64-2

Tuning the structure of pyridinolate-based functional ionic liquids for highly efficient SO2 absorption was written by Cui, Guokai;Lyu, Shuzhen;Wang, Huiyong;Li, Zhiyong;Zhang, Ruina;Wang, Jianji. And the article was included in Fuel in 2021.Reference of 626-64-2 This article mentions the following:

A series of pyridinolate anion-functional ionic liquids (ILs) containing different kinds of cations were designed and prepared, including tri-n-hexyltetradecylphosphonium [P66614], tri-n-butylethylphosphonium [P4442], and 1,1,3,3-tetramethylguandinium [TMG] cations and pyridinolate [PyO] anions with different N positions. Densities and viscosities at different temperatures were measured because of their importance for the absorption of SO2. Effect of different structures on the absorption of SO2 was studied, including the type and the alkyl chain length of cations, and the N positions of [PyO] anions (2-, 3-, and 4-). Addnl., effects of SO2 concentration and temperature for absorption were investigated. Especially, up to 6.00 and 2.53 mol SO2 per mol IL could be obtained by [P66614][4-PyO] at 1 bar and 0.1 bar of SO2, resp., when absorptions performed at 20°C. The results indicate that (1) the aprotic cations weakened the cation···anion interaction and resulted in the released active sites on the anions, and (2) N position has an influence on charge distribution of [PyO] anions and resulted in the tunable absorption of SO2. Reversible SO2 absorption and [P66614][4-PyO] regeneration could be performed several times without losing efficiency. Furthermore, the mechanism of absorption was studied through FT-IR and NMR methods and the results showed that the absorption of SO2 by [P66614][4-PyO] includes physisorption and chemisorption. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Reference of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Reference of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Paul, Melanie et al. published their research in Chemistry – A European Journal in 2020 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.HPLC of Formula: 626-64-2

Exceptional Substrate Diversity in Oxygenation Reactions Catalyzed by a Bis(μ-oxo) Copper Complex was written by Paul, Melanie;Teubner, Melissa;Grimm-Lebsanft, Benjamin;Golchert, Christiane;Meiners, Yannick;Senft, Laura;Keisers, Kristina;Liebhaeuser, Patricia;Roesener, Thomas;Biebl, Florian;Buchenau, Soeren;Naumova, Maria;Murzin, Vadim;Krug, Roxanne;Hoffmann, Alexander;Pietruszka, Joerg;Ivanovic-Burmazovic, Ivana;Ruebhausen, Michael;Herres-Pawlis, Sonja. And the article was included in Chemistry – A European Journal in 2020.HPLC of Formula: 626-64-2 This article mentions the following:

The enzyme tyrosinase contains a reactive side-on peroxo dicopper(II) center as catalytically active species in C-H oxygenation reactions. The tyrosinase activity of the isomeric bis(μ-oxo) dicopper(III) form has been discussed controversially. The synthesis of bis(μ-oxo) dicopper(III) species [Cu2(μ-O)2(L1)2](X)2 ([O1](X)2, X = PF6–, BF4–, OTf–, ClO4–), stabilized by the new hybrid guanidine ligand 2-(2-((dimethylamino)methyl)phenyl)-1,1,3,3-tetramethylguanidine (L1), and its characterization by UV/Vis, Raman, and XAS spectroscopy, as well as cryo-UHR-ESI mass spectrometry, are described. The highlight selective oxygenation of a plethora of phenolic substrates such as 1H-indol-7-ol, naphthalen-1-ol, pyridin-4-ol, etc. mediated by [O1](PF6)2, results in mono- and bicyclic quinones such as 3,4-pyridinedione, 1,2-naphthalenedione, 1H-indole-6,7-dione and provides an attractive strategy for designing new phenazines e.g., benzo[a]phenazine. The selectivity is predicted by using the Fukui function, which is hereby introduced into tyrosinase model chem. The bioinspired catalysis harnesses mol. dioxygen for organic transformations and achieves a substrate diversity reaching far beyond the scope of the enzyme. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2HPLC of Formula: 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.HPLC of Formula: 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Makino, Kosho et al. published their research in Synlett in 2019 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Related Products of 626-64-2

Chemoselective Demethylation of Methoxypyridine was written by Makino, Kosho;Hasegawa, Yumi;Inoue, Takahide;Araki, Koji;Tabata, Hidetsugu;Oshitari, Tetsuta;Ito, Kiyomi;Natsugari, Hideaki;Takahashi, Hideyo. And the article was included in Synlett in 2019.Related Products of 626-64-2 This article mentions the following:

A chemoselective demethylation method for various methoxypyridine derivatives I (R = 3-OMe, 4-CH2=CHCH2O, 4-C6H5CH2O, etc.; X = H, 5-Cl, 4-Me, etc.; Y = CH, N) has been developed. Treatment of 4-methoxypyridine with L-selectride in THF for 2 h at reflux temperature afforded 4-hydroxypyridine in good yield; and no reaction to anisole is occurred. The utility of this method was demonstrated by the efficient synthesis of the metabolic substances of the antiulcer agent omeprazole. Chemoselective demethylation at the site of 3,5-dimethyl-4-methoxypyridine in the presence of 4-methoxybenzimidazole was achieved. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Related Products of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Related Products of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem