Tag: 0-100

Response of intestinal metabolome to polysaccharides from mycelia of Ganoderma lucidum was written by Jin, Mingliang;Zhang, Hao;Wang, Jiaojiao;Shao, Dongyan;Yang, Hui;Huang, Qingsheng;Shi, Junling;Xu, Chunlan;Zhao, Ke. And the article was included in International Journal of Biological Macromolecules in 2019.Reference of 626-64-2 This article mentions the following:

Polysaccharides from the mycelia of Ganoderma lucidum (GLP) can improve intestinal barrier function, regulate intestinal immunity and modulate intestinal microbiota. In the present study, GLP was given via oral administration to rats (100 mg/kg body weight, 21 days) to investigate the metabolomic profiling of caecal contents induced by GLP. Gas chromatog.-time of light/mass spectrometry (GC-TOF/MS) was performed to identify the metabolites, followed by biomarker and pathway anal. The multivariate anal. indicated clear separated clusters between two groups. The significantly different metabolites were characterized, which mainly involved in vitamin B6 metabolism, pyrimidine metabolism, fructose and mannose metabolism, and alanine, aspartate and glutamate metabolism Indolelactate and 2,2-dimethylsuccinic acid were selected as key biomarkers responded to GLP administration. Furthermore, significantly different metabolites identified were associated with the improvement of intestinal immunol. function and regulation of intestinal microbiota. Our results provided a potential metabolomic mechanism of health-beneficial properties of polysaccharides from the mycelia of G. lucidum, which might be used as functional agents to regulate the intestinal functions. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Reference of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Reference of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Enhancement of nonlinearity by a parasubstituted compounds – it’s spectroscopic analysis was written by Anandhi, S.;Shyju, T. S.. And the article was included in Materials Today: Proceedings in 2021.Application of 626-64-2 This article mentions the following:

By slow cooling solution growth technique, transparent single crystals of 4-pyridone 4-nitrophenol (4PNP) were grown using ethanol as solvent. The harvested crystals were subjected to various characterization studies. Single crystal XRD reveals that the grown crystal crystallizes in orthorhombic system. The grown crystals were characterized by FTIR/Raman to ascertain the fundamental functional groups. Theor. anal. predicts that 324 possible optical modes of vibrations. Bandgap and refractive index were obtained from the UV-Vis optical studies. Fluorescence spectrum shows an emissive peak at 340 nm. HOMO-LUMO plot reports the energy gap on the basis of MO energy levels. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Application of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chemical Differentiation of Sugarcane Cultivars Based on Volatile Profile and Chemometric Analysis was written by Silva, Pedro;Freitas, Jorge;Nunes, Fernando M.;Camara, Jose S.. And the article was included in Journal of Agricultural and Food Chemistry in 2021.Name: Pyridin-4-ol This article mentions the following:

Sugarcane (SC) is a perennial grass widely cultivated in tropical and subtropical regions. However, its cultivation in Europe is residual, where Madeira Island, Portugal, is the only region where SC continues to be extensively cultivated. For the first time, the volatile profiles of regional cultivars were established by solid-phase microextraction combined with gas chromatog.-mass spectrometry. Different volatile profiles for each cultivar were recognized, identifying 260 volatile organic compounds belonging to 15 chem. classes, such as aldehydes, alcs., ketones, hydrocarbons, esters, and terpenes. Chemometric anal. procedure, namely, one-way ANOVA with Tukey’s test, principal component anal., partial least-square anal., linear discriminant anal., and hierarchical clustering anal., allowed the differentiation between all regional cultivars. This study represents an important contribution for the maintenance of biodiversity and subsistence of the SC industry in Europe. Furthermore, it is also a valuable contribution to establish the typicality of traditional SC-based products, such as SC honey. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Name: Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Name: Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nickel-catalyzed oxidative hydroxylation of arylboronic acid: Ni(HBTC)BPY MOF as an efficient and ligand-free catalyst to access phenolic motifs was written by Latha, Ganesapandian;Devarajan, Nainamalai;Karthik, Murugan;Suresh, Palaniswamy. And the article was included in Catalysis Communications.Recommanded Product: 626-64-2 This article mentions the following:

A straightforward and mild oxidative ipso-hydroxylation of arylboronic acids was achieved using a simple and non-noble metal, nickel-based reusable heterogeneous catalyst Ni(HBTC)BPY MOF (HBTC = benzene-1,3,5-tricarboxylate, BPY = 4,4′-bipyridine) in the presence of benign hydrogen peroxide as an oxidant under ambient reaction condition. The Ni(HBTC)BPY MOF exhibited excellent catalytic activity towards the formation of phenols from diverse arylboronic acids within short time and was reused up to five times without any notable loss in its activity as well as shown high functional group tolerance even in the presence of sensitive functionalities and useful to achieve hydroxyl group in heterocycles. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Recommanded Product: 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Recommanded Product: 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Biological insights into the piericidin family of microbial metabolites was written by Azad, Sepideh. M.;Jin, Yu;Ser, Hooi-Leng;Goh, Bey-Hing;Lee, Learn-Han;Thawai, Chitti;He, Ya-Wen. And the article was included in Journal of Applied Microbiology in 2022.Application In Synthesis of Pyridin-4-ol This article mentions the following:

Extensively produced by members of the genus Streptomyces, piericidins are a large family of microbial metabolites, which consist of main skeleton of 4-pyridinol with methylated polyketide side chain. Nonetheless, these metabolites show differences in their bioactive potentials against micro-organisms, insects and tumor cells. Due to its close structural similarity with coenzyme Q, piericidins also possess an inhibitory activity against NADH dehydrogenase as well as Photosystem II. This studied the latest research progress of piericidins, covering the chem. structure and phys. properties of newly identified members, bioactivities, biosynthetic pathway with gene clusters and future prospect. With the increasing incidence of drug-resistant human pathogen strains and cancers, this aimed to provide clues for the development of either new potential antibiotics or anti-tumor agents. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application In Synthesis of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Application In Synthesis of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hydrothermal carbonization of spent mushroom compost waste compared against torrefaction and pyrolysis was written by Atallah, Emile;Zeaiter, Joseph;Ahmad, Mohammad N.;Leahy, James J.;Kwapinski, Witold. And the article was included in Fuel Processing Technology in 2021.Formula: C5H5NO This article mentions the following:

The effects of operating conditions (temperature, residence time, and water contents) of hydrothermal carbonization (HTC) of spent mushroom compost (SMC) waste on the hydrochars (HCs) and liquid effluent characteristics were exptl. revised and ranked in increasing order: residence time < dilution factor < temperature HTC upgraded the energy capabilities by doubling their heating values and increasing their fixed carbon contents four times. HTC also enhanced the soil amendment characteristics of SMC feedstock in terms of increasing the adsorption polar heads concentration, enriching its calcium and heavy metals contents after a thorough inorganic contents evaluation, doubling the surface area and increasing the pore size by a factor of five. When compared against biocoal from torrefaction in another study, HCs contained less toxic oxygenated compounds and had an 11% higher HHV at lower temperature (i.e. lower energy cost). On the other hand, HCs showed higher surface area (25 m2/g at 250 °C in HTC compared to 16 m2/g at 550 °C in pyrolysis), close adsorption characteristic, and comparable energy capabilities (22.72 MJ/kg at 700 °Cs in pyrolysis compared to 20.7 MJ/kg at 250 °C in HTC) to pyrolysis at significantly lower temperature GCMS along with UV were used to verify the reviewed degradation mechanism and evaluate the effect of process parameters on this mechanism and on the composition and toxicity of the HTC liquid effluent. They showed that acetic and formic acids, ethanol, phenol, and acetaldehyde were the major compounds that had resulted from the degradation of cellulose, hemicellulose, and lignin. Their concentrations increased with temperature and residence time, but was dependent on temperature in the case of increasing the dilution factor. Nevertheless, HTC degradation enhanced the total acids-phenols concentration in the liquid effluent by 700%. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Formula: C5H5NO).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Formula: C5H5NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Different bonds cleavage of arenesulfonates: access to diverse aryl ethers was written by Fang, Yongsheng;Li, Wenhui;Lin, Jianying;Li, Xing. And the article was included in Huaxue Xuebao in 2021.Computed Properties of C5H5NO This article mentions the following:

Aryl alkyl ethers and diaryl ethers represent ubiquitous structural motifs in natural products, medicinally relevant compounds, biol. active compounds, agrochems. and organic materials, and they are also useful building blocks in organic synthesis. Therefore, many transformations have been reported for the synthesis of these two kinds of compounds Among these versatile methods, transition-metal-free approaches using different reagents as starting materials have been developed as promising and alternative protocols. Although one example for transition-metal-catalyzed transformation of arenesulfonates into aryl alkyl ethers and diaryl ethers has been reported, there are no reports about the formation of aryl ethers utilizing arenesulfonates as starting materials via a transition-metal-free protocol, and existing methods for providing sterically hindered ortho-substituted diaryl ethers using electrophiles substituted by electron-deficient groups, particularly by a bulky one at the ortho-position as starting materials are very rare. We will report a K₂CO₃-mediated method for the synthesis of aryl alkyl ethers using arenesulfonates as starting materials via two alternative paths. One path is the cross-coupling of aryl arenesulfonates with alcs. through their S-O bond cleavage, and the other uses the reactions of alkyl arenesulfonates with phenols via their C-O bond cleavage. Addnl., we also report the K₃PO₄^–promoted preparation of bulky ortho-substituted diaryl ethers via the C-S bond cleavage of aryl arenesulfonates or arenesulfonyl chlorides bearing electron-withdrawing groups at 2-, 2,4- or 2,6-position of the Ph ring in the presence of phenols, resp. General procedure for the reactions of aryl arenesulfonates with various alcs.: to an oven-dried glass tube, aryl arenesulfonate 1 (0.2 mmol), K₂CO₃ (2 equivalent) and 0.5 mL alc. 2 were added in turn. The reaction system was then stirred at 65°C until the aryl arenesulfonate 1 was completely consumed as determined by thin layer chromatog. Finally, the reaction mixture was purified by silica gel column chromatog. to afford the desired product 3. General procedure for the reactions of aryl o-substituted arenesulfonates with the corresponding phenols: to an oven-dried glass tube, aryl o-substituted arenesulfonate 7 (0.2 mmol), K₃PO₄ (3 equivalent), the corresponding phenol 5 (1.2 equivalent) and 1.0 mL toluene were added in turn. The reaction system was then stirred at 100°C until the reaction was over as determined by TLC. Finally, the reaction mixture was purified by silica gel column chromatog. to afford the desired product 8. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Computed Properties of C5H5NO).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Computed Properties of C5H5NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A metabolomic approach to investigate effects of ocean acidification on a polar microalga Chlorella sp. was written by Tan, Yong-Hao;Lim, Phaik-Eem;Beardall, John;Poong, Sze-Wan;Phang, Siew-Moi. And the article was included in Aquatic Toxicology in 2019.Related Products of 626-64-2 This article mentions the following:

Ocean acidification, due to increased levels of anthropogenic carbon dioxide, is known to affect the physiol. and growth of marine phytoplankton, especially in polar regions. However, the effect of acidification or carbonation on cellular metabolism in polar marine phytoplankton still remains an open question. There is some evidence that small chlorophytes may benefit more than other taxa of phytoplankton. To understand further how green polar picoplankton could acclimate to high oceanic CO₂, studies were conducted on an Antarctic Chlorella sp. Chlorella sp. maintained its growth rate (∼0.180 d^-1), photosynthetic quantum yield (Fv/Fm = ∼0.69) and chlorophyll a (0.145 fg cell^-1) and carotenoid (0.06 fg cell^-1) contents under high CO₂, while maximum rates of electron transport decreased and non-photochem. quenching increased under elevated CO₂. GCMS-based metabolomic anal. reveal that this polar Chlorella strain modulated the levels of metabolites associated with energy, amino acid, fatty acid and carbohydrate production, which could favor its survival in an increasingly acidified ocean. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Related Products of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Related Products of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reaction parameters effect on hydrothermal liquefaction of castor (Ricinus Communis) residue for energy and valuable hydrocarbons recovery was written by Kaur, Ravneet;Gera, Poonam;Jha, Mithilesh Kumar;Bhaskar, Thallada. And the article was included in Renewable Energy in 2019.Safety of Pyridin-4-ol This article mentions the following:

Castor plant (Ricinus communis) is a fast growing, perennial shrub also known as wonder tree from Euphorbiaceae family. India ranks globally first with production of 87% of the castor seed, while second and third largest producer countries, China and Brazil produced 5% and 1%, resp. Hydrothermal liquefaction (HTL) is one of the most promising thermochem. conversion process used to convert wet/high moisture biomass to biofuels and value-added hydrocarbons. HTL of castor residue (stem and leaves) was performed at 260, 280, 300 °C and 15, 30, 60, 90 min. Investigations on the effect of temperature and residence time on distribution of products (bio-oil, bio-char) indicated the maximum Total Bio-oil (TBO) yield of c.a. 15.8 wt% was obtained at 300 °C at 60 min. The major compounds observed by GC-MS were phenols and their derivatives, aromatic hydrocarbons, N-containing compounds, acids. In addition, the recovery of carbon and corresponding energy recovery with respect to castor residue indicated that the carbon and energy recovery for bio-oil 1 were 24.23% and 31.08% resp. An increase in the carbon and decrease of oxygen content in bio-oil (BO) demonstrates that the castor residue can be used as a potential feedstock for bioenergy applications. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Safety of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Safety of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of Electron-Rich Covalent Organic Frameworks COF-JLU25 for Photocatalytic Aerobic Oxidative Hydroxylation of Arylboronic Acids to Phenols was written by Xiao, Guangjun;Li, Wenqian;Chen, Tao;Hu, Wei-Bo;Yang, Hui;Liu, Yahu A.;Wen, Ke. And the article was included in European Journal of Organic Chemistry in 2021.Application In Synthesis of Pyridin-4-ol This article mentions the following:

Visible-light-driven organic reactions are environmentally friendly green chem. transformations among which photosynthetic oxidative hydroxylation of arylboronic acids to phenols has attracted increasing research interest during the very recent years. Given the efficiency and reusability of heterogeneous catalysts, COF-JLU25, an electron-rich COF-based photocatalyst constructed by integrating electron-donating blocks 1,3,6,8-tetrakis(4-aminophenyl)pyrene (PyTA) and 4-[4-(4-formylmethyl)-2,5-dimethoxyphenyl] benzaldehyde (TpDA), was selected as a photocatalyst for the oxidative hydroxylation of arylboronic acids. In our studies, COF-JLU25 demonstrated excellent photocatalytic activity with high efficiency, robust reusability, and low catalyst loading, showcasing an application potential of previously underexplored COF-based photocatalyst composed solely of electron-rich units. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application In Synthesis of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application In Synthesis of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem