Tag: 100-200

Preparation of Pyridinium-Functionalized Magnetic Adsorbent and Its Application for Nitrate Removal from Aqueous Solution was written by Ma, F.;Du, H. T.;Wang, Q.;Li, R. H.;Zhang, Z. Q.. And the article was included in Water, Air, & Soil Pollution in 2015.Synthetic Route of C5H6ClN This article mentions the following:

A novel magnetic pyridinium-functionalized mesoporous silica adsorbent (Fe₃O₄@SiO₂@Py-Cl) was synthesized for nitrate removal from aqueous solutions The adsorption performances were investigated by varying exptl. conditions such as pH, contact time, and initial concentration The adsorbent was characterized by transmission electron microscopy (TEM), XPS, Fourier transform IR (FT-IR) spectroscopy, and magnetic hysteresis loops. The results showed that the adsorption equilibrium could be reached within 30 min and the kinetic data were fitted well by pseudo-second-order and intra-particle diffusion model. The adsorbent exhibited a favorable performance, and its maximum adsorption capacity calculated by the Langmuir isotherm model was 1.755 mmol/g. The nitrate adsorption mechanism was mainly controlled by the material through ion exchange of nitrate with chloridion, as determined by XPS. This study indicated that this novel pyridinium-functionalized mesoporous material had excellent adsorption capacity. Meanwhile, compared with other adsorbents, it could remove nitrate fast and easy to be collected by magnetic separation, showing great potential application for nitrate removal from aqueous solution In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Synthetic Route of C5H6ClN).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six 锜?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H鐪塩kel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Synthetic Route of C5H6ClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The synthesis of 4-benzylamino-6-methyl-1H-pyrrolo[3,2-c]pyridine and 4-benzylamino-6-methyl-1H-pyrrolo[2,3-b]pyridine was written by Meade, Eric A.;Beauchamp, Lilia M.. And the article was included in Journal of Heterocyclic Chemistry in 1996.Category: pyridine-derivatives This article mentions the following:

Deaza analogs of 2-methyl-N-(phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, i.e., 6-methyl-N-(phenylmethyl)-1H-pyrrolo[3,2-c]pyridin-4-amine (I) and 6-methyl-N-(phenylmethyl)-1H-pyrrolo[2,3-b]pyridin-4-amine (II) were prepared The 1-deaza analog I was prepared via a multi-step procedure from a pyrrole precursor, 1-benzyl-2-formylpyrrole, while the 3-deaza analog II was synthesized from 2-amino-3,6-dimethylpyridine. I and II were found to be devoid of anxiolytic activity. In the experiment, the researchers used many compounds, for example, 3,6-Dimethyl-2-pyridinamine (cas: 823-61-0Category: pyridine-derivatives).

3,6-Dimethyl-2-pyridinamine (cas: 823-61-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Efficient total synthesis of neocryptolepine and synthetic access to 6-methylquinindoline from a common intermediate was written by Mendez, Maria V.;Heredia, Daniel A.;Larghi, Enrique L.;Bracca, Andrea B. J.;Kaufman, Teodoro S.. And the article was included in RSC Advances in 2017.SDS of cas: 628-13-7 This article mentions the following:

A convenient approach toward the indoloquinolines neocryptolepine and 6-methylquinindoline from a common intermediate, is reported. Both sequences, designed for maximum use of accessible reagents and robust conditions, are straightforward and efficient. They involved the amidation of 2-aminobenzaldehyde (prepared by iron-mediated reduction of 2-nitrobenzaldehyde) with 2-nitrophenylacetic acid, followed by a K₂CO₃-assisted cyclization to form a 3-(2-nitrophenyl)quinolin-2-one as the common precursor. Me₂CO₃-mediated N-methylation of the lactam, reduction of the nitro moiety and final cyclization resulted in 55% overall yield of neocryptolepine, whereas cyclocondensation and N-methylation afforded 79% overall yield of 6-Me quinindoline. Thus, the sequences toward the targets entailed two POCl₃-promoted C-N bond forming reactions, two Fe-mediated nitro group reductions and two base-promoted transformations. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7SDS of cas: 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of 閳?8.7 鑴?10閳? cm3璺痬ol閳?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ璺痬ol閳? in the liquid phase and 140.4 kJ璺痬ol閳? in the gas phase. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.SDS of cas: 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Investigation of reaction conditions in the synthesis of imidazolium, pyridinium and pyrrolidinium based ionic liquids was written by Adibi, M.;Mehdizadeh, A.;Ahmadi, A. N.. And the article was included in Pazhuhesh Naft in 2009.Recommanded Product: 125652-55-3 This article mentions the following:

Unique properties of ionic liquids such as low vapor pressure, high thermal stability, and their ability to dissolve polar compounds makes them potential alternatives for organic solvents lacking such characteristics. Studies show that substantial efforts are being made to synthesize these ionic liquids under milder reaction conditions. Quaternary imidazolium, pyridinium, and pyrrolidinium based salts are unfortunately prepared at high temperatures over long periods of time, making the syntheses economically inefficient. Parameters involved in the synthesis of each of these salts have been optimized in this work and the synthesis conditions have been compared. Results indicate that the synthesis of dialkyl imidazolium chlorides I (R = n-C₄H₉, n-C₆H₁₃, n-C₈H₁₇) gives higher yields and requires shorter reaction times in comparison with the other two groups. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3Recommanded Product: 125652-55-3).

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six 锜?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H鐪塩kel criteria for aromatic systems. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Recommanded Product: 125652-55-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Highly active recyclable heterogeneous Pd/ZnO nanoparticle catalyst: sustainable developments for the C-O and C-N bond cross-coupling reactions of aryl halides under ligand-free conditions was written by Hosseini-Sarvari, Mona;Razmi, Zahra. And the article was included in RSC Advances in 2014.Product Details of 4783-68-0 This article mentions the following:

Efficient Pd supported on ZnO nanoparticles for the ligand-free O-arylation and N-arylation of phenols and various N-H heterocycles with aryl chlorides, bromides, and iodides were readily synthesized and characterized. The amount of palladium on ZnO was 9.84 wt% (0.005 g of the catalyst contains 462 x 10^-8 mol% of Pd) which was determined by ICP anal. This nano sized Pd/ZnO with an average particle size of 20-25 nm and sp. surface area 40.61 m² g^-1 was used as a new reusable heterogeneous catalyst for the formation of C-O and C-N bonds in organic synthesis. This protocol gave the arylated product in satisfactory yields without any N₂ or Ar flow. The catalyst was recovered and recycled several times without marked loss of activity. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Product Details of 4783-68-0).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Product Details of 4783-68-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Expeditious and Solvent-Free Nickel-Catalyzed C-H Arylation of Arenes and Indoles was written by Jagtap, Rahul A.;Soni, Vineeta;Punji, Benudhar. And the article was included in ChemSusChem in 2017.Synthetic Route of C12H11N This article mentions the following:

An efficient solvent-free nickel-catalyzed method for C-H bond arylation of arenes and indoles was developed, which proceeds expeditiously through chelation assistance. The reaction is highly selective for mono-arylation and tolerates sensitive and structurally diverse functionalities, such as halides, ethers, amines, indole, pyrrole and carbazole. This reaction represents the first example of a nickel-catalyzed C-H arylation by monochelate assistance and symbolizes a rare precedent in solvent-free C-H arylation. Mechanistic studies by various controlled reactions, kinetic studies, and deuterium labeling experiments suggest that the arylation follows a single electron transfer (SET) pathway involving the turnover-limiting C-H nickelation process. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Synthetic Route of C12H11N).

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Synthetic Route of C12H11N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Three-Point Hydrogen Bonding Assembly between a Conjugated PPV and a Functionalized Fullerene was written by Fang, Hongjuan;Wang, Shu;Xiao, Shengqiang;Yang, Junlin;Li, Yuliang;Shi, Zhiqiang;Li, Hongmei;Liu, Huibiao;Xiao, Shengxiong;Zhu, Daoben. And the article was included in Chemistry of Materials in 2003.Product Details of 1075-62-3 This article mentions the following:

A new self-assembly system between a PPV derivative and an organofullerene through a three-point hydrogen-bonding interaction was prepared The formation of hydrogen bonding was confirmed by ¹H NMR studies in CDCl₃. Fluorescence quenching experiments indicated that the fluorescence of uracil-containing polyphenylenevinylene derivative U-PPV was greatly quenched by 2,6-diacylamidopyridine-containing compound DAP-C₆₀ (K_SV = 5.8 鑴?10⁴ M^-1). In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3Product Details of 1075-62-3).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Product Details of 1075-62-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Co-oxidation of isomeric alkylpyridines was written by Matvienko, A. G.;Zalevskaya, N. M.;Efimova, I. V.;Nazarov, N. N.;Opeida, I. A.. And the article was included in Kinetika i Kataliz in 1984.Application In Synthesis of 2-Isopropylpyridine This article mentions the following:

The liquid-phase oxidation of binary mixtures of 3-isopropylpyridine with 2-, 3-, and 4-ethylpyridine and PhEt and of 3-ethylpyridine with isomeric isopropylpyridines was studied at 348 K. The results were combined with literature data to obtain rate constants for reactions of peroxy radicals with alkylpyridines and PhEt. The reactivity of isopropylpyridines toward primary and secondary peroxy radicals increased in the order 4- < 2- < 3-isomer; cumene was more reactive. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Application In Synthesis of 2-Isopropylpyridine).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Application In Synthesis of 2-Isopropylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Novel 1,4-dihydropyridine calcium antagonists. I. Synthesis and hypotensive activity of 4-(substituted pyridyl)-1,4-dihydropyridine derivatives was written by Ashimori, Atsuyuki;Ono, Taizo;Uchida, Takeshi;Ohtaki, Yutaka;Fukaya, Chikara;Watanabe, Masahiro;Yokoyama, Kazumasa. And the article was included in Chemical & Pharmaceutical Bulletin in 1990.SDS of cas: 116308-35-1 This article mentions the following:

A series of 4-(substituted pyridyl)-1,4-dihydropyridine derivatives I (R = H, halo, CF₃, etc.) were synthesized and their hypotensive effects examined Several compounds have a hypotensive activity parallel to that of nicardipine; the 4-(3-trifluoromethyl-2-pyridyl) and 4-(2-trifluoromethyl-3-pyridyl) derivatives, in particular, had approx. twice the duration of nicardipine, and the 4-(4-cyano-2-pyridyl) derivative had the most potent hypotensive activity of all the derivatives synthesized. In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1SDS of cas: 116308-35-1).

2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.SDS of cas: 116308-35-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Valorization of chitin derived N-acetyl-D-glucosamine into high valuable N-containing 3-acetamido-5-acetylfuran using pyridinium-based ionic liquids was written by Zang, Hongjun;Lou, Jing;Jiao, Shuolei;Li, Huanxin;Du, Yannan;Wang, Jiao. And the article was included in Journal of Molecular Liquids in 2021.Safety of Pyridinehydrochloride This article mentions the following:

A series of pyridinium-based ionic liquids were synthesized to directly catalyze the conversion of N-acetyl-D-glucosamine (NAG, the monomer of chitin) to 3-acetamido-5-acetylfuran (3A5AF). The yield of 3A5AF in 1-carboxymethyl pyridinium chloride ionic liquid reached 37.49%, without any additives. Using B₂O₃ and CaCl₂ as additives, the optimum yield increased to 67.37% at 180鎺矯 in 20 min. In addition, HPLC-MS anal. was utilized to elucidate the reaction mechanism. The research on turning “waste” into “wealth” opens up new ways for the utilization of biomass waste, which not only reduces environmental pollution but also has potential economic value. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Safety of Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Safety of Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem