Tag: 100-200

Fershtat, Leonid L. et al. published their research in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2015 | CAS: 15128-90-2

3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C閳ユ弻 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Recommanded Product: 15128-90-2

Synthesis of heteroarylsulfanyl- and heteroaryloxyfuroxans by nucleophilic substitution of nitro group in nitrofuroxans with heterocyclic thiol and hydroxy derivatives* was written by Fershtat, Leonid L.;Epishina, Margarita A.;Kulikov, Alexander S.;Struchkova, Marina I.;Makhova, Nina N.. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2015.Recommanded Product: 15128-90-2 This article mentions the following:

A general method for the synthesis of heteroaryl- and heteroaryloxyfuroxans, e.g., I, based on nucleophilic substitution of 4-nitrofuroxans with heterocyclic thiols and alcs. in 1,8-diazabicyclo[5.4.0]undec-7-ene/MeCN system at room temperature is reported. Hetarylthiols reacted with 4-nitrofuroxans containing aliphatic, benzyl, and aromatic substituents at the ring C-3 atom, allowing to obtain a library of heteroarylsulfanylfuroxans, while the reaction with hydroxy heterocycles was successful only in the case of 4-nitro-3-phenylfuroxan, the rest of the nitrofuroxans showing low reactivity, and substitution products could be obtained only in certain cases. 4-Nitrofuroxans with electron-withdrawing substituents (NO2, CONH2) acted as oxidants, forming 1,2-di(heteroaryl)disulfides. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2Recommanded Product: 15128-90-2).

3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C閳ユ弻 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Recommanded Product: 15128-90-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yuan, Yi et al. published their research in Inorganic Chemistry in 2020 | CAS: 91-02-1

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 91-02-1

Iridium(III) Complexes Bearing a Formal Tetradentate Coordination Chelate: Structural Properties and Phosphorescence Fine-Tuned by Ancillaries was written by Yuan, Yi;Gnanasekaran, Premkumar;Chen, Yu-Wen;Lee, Gene-Hsiang;Ni, Shao-Fei;Lee, Chun-Sing;Chi, Yun. And the article was included in Inorganic Chemistry in 2020.Recommanded Product: 91-02-1 This article mentions the following:

Synthesis of the multidentate coordinated chelate N3C-H2, composed of a linked functional pyridyl pyrazole fragment plus a peripheral Ph and pyridyl unit, was obtained using a multistep protocol. Preparation of Ir(III) metal complexes bearing a N3C chelate in the tridentate (榄?sup>3), tetradentate (榄?sup>4), and pentadentate (榄?sup>5) modes was executed en route from two nonemissive dimer intermediates [Ir(榄?sup>3-N3CH)Cl2]2 (1) and [Ir(榄?sup>4-N3C)Cl]2 (2). Next, a series of mononuclear Ir(III) complexes with the formulas [Ir(榄?sup>4-N3C)Cl(py)] (3), [Ir(榄?sup>4-N3C)Cl(dmap)] (4), [Ir(榄?sup>4-N3C)Cl(mpzH)] (5), and [Ir(榄?sup>4-N3C)Cl(dmpzH)] (6), as well as diiridium complexes [Ir2(榄?sup>5-N3C)(mpz)2(CO)(H)2] (7) and [Ir2(榄?sup>5-N3C)(dmpz)2(CO)(H)2] (8), were obtained upon treatment of dimer 2 with pyridine (py), 4-dimethylaminopyridine (dmap), 4-methylpyrazole (mpzH), and 3,5-dimethylpyrazole (dmpzH), resp. These Ir(III) metal complexes were identified using spectroscopic methods and by x-ray crystallog. anal. of representative derivatives 3, 5, and 7. Their photophys. and electrochem. properties were investigated and confirmed by the theor. simulations. Notably, green-emitting organic light-emitting diode (OLED) on the basis of Ir(III) complex 7 gives a maximum external quantum efficiency up to 25.1%. This result sheds light on the enormous potential of this tetradentate coordinated chelate in the development of highly efficient iridium complexes for OLED applications. Preparation of Ir(III) complexes bearing tailor-made multidentate N3C chelate are reported, from which a green-emitting OLED with a maximum EQE of 25.1% was successfully fabricated using diiridium complex 7. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Recommanded Product: 91-02-1).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 91-02-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Russell, Glen A. et al. published their research in Journal of Organic Chemistry in 1985 | CAS: 644-98-4

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. HPLC of Formula: 644-98-4

Alkylation of pyridine in free radical chain reactions utilizing alkylmercurials was written by Russell, Glen A.;Guo, Deliang;Khanna, Rajive K.. And the article was included in Journal of Organic Chemistry in 1985.HPLC of Formula: 644-98-4 This article mentions the following:

Pyridines or N,N,N‘,N‘-tetramethyl-p-phenylenediamine will undergo a photostimulated free radical chain reaction with alkylmercury halides or carboxylates yielding ring alkylated substitution products. Alkene mercuration products can be used without isolation for the alkylation reaction. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4HPLC of Formula: 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. HPLC of Formula: 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wan, Ting et al. published their research in ChemCatChem in 2019 | CAS: 4373-61-9

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Related Products of 4373-61-9

Rh(III)-Catalyzed Regioselective Acetylation of sp2 C-H Bond Starting from Paraformaldehyde was written by Wan, Ting;Du, Sidong;Pi, Chao;Wang, Yong;Li, Rongbin;Wu, Yangjie;Cui, Xiuling. And the article was included in ChemCatChem in 2019.Related Products of 4373-61-9 This article mentions the following:

Rh(III)-catalyzed acetylation of sp2 C-H bonds has been realized using paraformaldehyde as an acetylating reagent. This procedure features simultaneous formation of two C-C bonds, external oxidants free, and water as the sole byproducts, thus offering an environmentally benign acetylation of arenes R1R2 (R1 = pyridin-2-yl, 4-methylpyridin-2-yl, isoquinolin-1-yl; R2 = Ph, 3-bromophenyl, 2,3-dihydro-1,4-benzodioxin-5-yl, etc.). A range of functional groups tolerance was observed In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Related Products of 4373-61-9).

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Related Products of 4373-61-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tori, Kazuo et al. published their research in Tetrahedron Letters in 1973 | CAS: 3718-65-8

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Quality Control of 3,5-Dimethylpyridine 1-oxide

Contact term contribution to lanthanide induced shifts in proton and carbon-13 NMR spectra of pyridine N-oxides was written by Tori, Kazuo;Yoshimura, Yohko;Kainosho, Masatsune;Ajisaka, Katsumi. And the article was included in Tetrahedron Letters in 1973.Quality Control of 3,5-Dimethylpyridine 1-oxide This article mentions the following:

Shifts induced by M(FOD)3, Eu(PTA)3, and M(DPM)3 (M = Eu, Pr, HFOD = 1,1,1,2,2,3,3-heptafluoro-7,7-dimethyloctane-4,6-dione, HPTA = pivaloyltrifluoroacetone, HDPM = dipivaloylmethane) in the 1H and 13C NMR of pyridine N-oxide and its alkyl derivatives included a contact term contribution. Upfield shifts were observed for the 灏?H and 绾?Me PMR signals and the directions of 13C shifts were those predicted for contact interaction. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Quality Control of 3,5-Dimethylpyridine 1-oxide).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Quality Control of 3,5-Dimethylpyridine 1-oxide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lorente, Almudena et al. published their research in Energy Conversion and Management in 2019 | CAS: 644-98-4

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Electric Literature of C8H11N

Analysis and optimisation of a novel “bio-brewery” approach: Production of bio-fuels and bio-chemicals by microwave-assisted, hydrothermal liquefaction of brewers’ spent grains was written by Lorente, Almudena;Remon, Javier;Budarin, Vitaliy L.;Sanchez-Verdu, Prado;Moreno, Andres;Clark, James H.. And the article was included in Energy Conversion and Management in 2019.Electric Literature of C8H11N This article mentions the following:

This work firstly explores the feasibility of using a novel microwave-assisted, catalyzed, hydrothermal process for the valorisation of brewers’ spent grains (BSGs), examining the effects of the temperature (180-250鎺矯), pressure (50-130 bar), reaction time (0-2 h) and catalyst amount (Ni-Co/Al-Mg, 0-0.25 g cat/g biomass). This route turned out to be a very promising approach for the production of bio-fuels (bio-oil and bio-char) and platform chems. (sugar rich aqueous solutions) in a single unit, helping the development of an innovative bio-refinery around BSGs. The overall conversion and the yields to gas, aqueous fraction and bio-oil varied by 31-68%, 10-33%, 9-48% and 4-14%, resp. The bio-oil was made up a complex mixture of phenols (0-26%), ketones (0-80%), aldehydes (0-57%), carboxylic acids (0-18%) and nitrogen compounds (0-76%). The proportions of C, H, N and O in the bio-oil varied as follow: 15-61 wt%, 5-10 wt%, 1-6 wt% and 26-77 wt%, resp., which shifted its higher heating value (HHV) between 9 and 27 MJ/kg. The liquid fraction comprised a mixture of DP > 6 oligosaccharides (67-98 C-weight%), DP2-6 oligosaccharides (0-10 C-weight%), saccharides (0.2-7 C-weight%), carboxylic acids (0-7 C-weight%) and furans (0-27 C-weight%). The spent solid after the experiments resembled an energetic like bio-char product, whose proportions of C, H, O and N varied by 35-72 wt%, 4-8 wt%, 1-4 wt% and 18-57 wt% and its HHV shifted between 9 and 32 MJ/kg. The optimization of the process revealed that using a temperature of 250鎺矯 and a pressure of 125 bar for 2 h, it is possible to convert the original material into high-energy biofuels: (8%) bio-oil (26 MJ/kg) and (35%) bio-char (32 MJ/kg); together with a (31%) saccharide-rich (>99 C-weight%) aqueous solution, thus converting this process into a very promising approach to achieve an environmentally-friendly and integral valorisation of brewers’ spent grains. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Electric Literature of C8H11N).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Electric Literature of C8H11N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Shin, Eun-Jae et al. published their research in Tetrahedron Letters in 2019 | CAS: 51834-97-0

5-Hydroxy-2-methoxylpyridine (cas: 51834-97-0) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 51834-97-0

Cooperation of biopolymer chitosan with hydrogen peroxide for ipso-hydroxylation of arylboronic acids under green conditions was written by Shin, Eun-Jae;Joo, Seong-Ryu;Kim, Seung-Hoi. And the article was included in Tetrahedron Letters in 2019.Recommanded Product: 51834-97-0 This article mentions the following:

Oxidative hydroxylation of arylboronic acids to the corresponding phenolic compounds R-OH [R = 2-MeC6H4, 2-naphthyl, 3-ClC6H4, etc.] under metal- and base-free aerobic conditions was successfully demonstrated using biopolymer support (chitosan or chitosan immobilized onto carbon nanotubes (CNT@Chitosan)). Hydrogen peroxide, as an eco-friendly oxidant, was compatible with the biopolymer supports and provided hydroxylation products in an efficient manner. The CNT@chitosan biopolymer support was particularly interesting for its potential recyclability. In the experiment, the researchers used many compounds, for example, 5-Hydroxy-2-methoxylpyridine (cas: 51834-97-0Recommanded Product: 51834-97-0).

5-Hydroxy-2-methoxylpyridine (cas: 51834-97-0) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 51834-97-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ni, Shengjun et al. published their research in Angewandte Chemie, International Edition in 2021 | CAS: 4783-68-0

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.SDS of cas: 4783-68-0

Mechanochemical Solvent-Free Catalytic C-H Methylation was written by Ni, Shengjun;Hribersek, Matic;Baddigam, Swarna K.;Ingner, Fredric J. L.;Orthaber, Andreas;Gates, Paul J.;Pilarski, Lukasz T.. And the article was included in Angewandte Chemie, International Edition in 2021.SDS of cas: 4783-68-0 This article mentions the following:

The mechanochem., solvent-free, highly regioselective, rhodium-catalyzed C-H methylation of (hetero)arenes is reported. The reaction shows excellent functional-group compatibility and is demonstrated to work for the late-stage C-H methylation of biol. active compounds The method requires no external heating and benefits from considerably shorter reaction times than previous solution-based C-H methylation protocols. Addnl., the mechanochem. approach is shown to enable the efficient synthesis of organometallic complexes that are difficult to generate conventionally. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0SDS of cas: 4783-68-0).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.SDS of cas: 4783-68-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chen, Qiang et al. published their research in Gaofenzi Cailiao Kexue Yu Gongcheng in 2011 | CAS: 59718-84-2

Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Computed Properties of C8H9NO2

Electro-generation of 3-methyl-2-formylaminopyridine in ferrocene modified bipolar membrane equipped cell was written by Chen, Qiang;Chen, Zhen;Wang, Yanhong;Zheng, Xi;Chen, Xiao;Chen, Riyao. And the article was included in Gaofenzi Cailiao Kexue Yu Gongcheng in 2011.Computed Properties of C8H9NO2 This article mentions the following:

The mSA-mCS bipolar membrane (BPM) was prepared by sodium alginate (SA) and chitosan (CS) modified by ferrocene and glutaraldehyde as linking reagents, resp., marked FSA-mCS BPM. FSA-mCS BPM was characterized by Fourier transform IR spectrum (FT-IR), I-V curves, OH– permeability. The interlayer property of the modified BPM was investigated by AC impedance. The FSA-mCS BPM was used as a separator in the electrolysis cell to prepare electro-generate 3-methyl-2-formylaminopyridine. The production yield is 60%, which is higher than that of Fe3+ modified mSA-mCS BPM or Nafion mono-membrane equipped cell. In the experiment, the researchers used many compounds, for example, Methyl 3-methylpicolinate (cas: 59718-84-2Computed Properties of C8H9NO2).

Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Computed Properties of C8H9NO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yao, Wubing et al. published their research in Journal of Organic Chemistry in 2020 | CAS: 4783-68-0

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Electric Literature of C11H9NO

Ru-Catalyzed ortho-Selective Diborylation of 2-Arylpyridines toward the Construction of 锜?Conjugated Functions was written by Yao, Wubing;Wang, Jiali;He, Lili;Cao, Dongdong;Yang, Jianguo. And the article was included in Journal of Organic Chemistry in 2020.Electric Literature of C11H9NO This article mentions the following:

A Ru catalytic ortho-C-H diborylation of 2-arylpyridine derivatives, including challenging 2-phenoxypyridine functions, using a remarkably low catalyst loading and a low-cost and bench-stable B source, was developed. The novel strategy shows high activity with excellent selectivity and may offer a versatile and green alternative to currently employed high loadings of noble metals or extra additives for the selective borylations. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Electric Literature of C11H9NO).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Electric Literature of C11H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem