Tag: 100-200

《A copper complex based catalytic conversion and isolation of carbonate from CO2 for the carbon sequestration process》 was published in Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) in 2020. These research results belong to Sivanesan, Dharmalingam; Seo, Bongkuk; Lim, Choong-Sun; Kim, Hyeon-Gook. Recommanded Product: Bis(pyridin-2-ylmethyl)amine The article mentions the following:

The conversion of CO2 into value-added chems. of industrial significance is of great interest due to global warming-related concerns and the depletion of natural resources. This paper describes a mononuclear copper complex with an N3S coordination environment that can catalyze the conversion of CO2 into the carbonate anion with an ambient O2. Electrochem. studies indicate that the N3S-ligated Cu(II) complex can be reduced to Cu(I), which can subsequently generate the carbonate anion from CO2 and ambient O2. In presence of LiClO4 when the N3S-ligated complex Cu(II) is reduced to Cu(I), the complex easily releases the carbonate anion which easily precipitates as Li2CO3 in CH3CN. These studies suggest that the N3S-ligated Cu(II)/(I) complexes can be used to convert CO2 to carbonate and isolate the generated carbonate. After reading the article, we found that the author used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Recommanded Product: Bis(pyridin-2-ylmethyl)amine)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. Recommanded Product: Bis(pyridin-2-ylmethyl)amine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Benazzi, Elisabetta; Begato, Federico; Niorettini, Alessandro; Destro, Lorenza; Wurst, Klaus; Licini, Giulia; Agnoli, Stefano; Zonta, Cristiano; Natali, Mirco published their research in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2021. The article was titled 《Electrocatalytic hydrogen evolution using hybrid electrodes based on single-walled carbon nanohorns and cobalt(II) polypyridine complexes》.Electric Literature of C12H13N3 The article contains the following contents:

The generation of hydrogen from water represents an important task towards a carbon neutral economy. Within this context, the preparation of hybrid electrodes merging the versatility of solid-state porous substrates and the catalytic ability and tunability of mol. complexes represents a great challenge. In the present work, we report on the preparation of hybrid cathodes for the hydrogen evolution reaction (HER) through an unprecedented combination of single-walled carbon nanohorns (SWCNHs) and two novel cobalt(II) polypyridine complexes based on the tris(2-pyridylmethyl)amine (TPMA) ligand scaffold. Suitable pyrene groups are introduced in the ligand framework in different positions to provide a way for direct anchoring onto the carbonaceous substrate by exploiting non-covalent π-π interactions. The present systems behave as competent cathodes for the HER in neutral aqueous solution with overpotentials of η ~0.5 V and stable current densities (within 1 h electrolysis) up to -0.50 mA cm-2, whose exact values depend on the catalyst used and are mainly related to the resp. loading on the electrode surface. In both cases, hydrogen evolution is detected under continuous electrolysis for up to ca. 12 h leading to maximum turnover numbers (TONs) of 4700 and 9180 molH2 molCo-1 for the two different complexes. The progressive deactivation under electrolytic conditions is mainly ascribed to leaching of the metal center from the polydentate ligand, likely occurring from the competent catalytic intermediates involved in the HER. In the experiment, the researchers used many compounds, for example, Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Electric Literature of C12H13N3)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. Electric Literature of C12H13N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Journal of Materials Chemistry C: Materials for Optical and Electronic Devices included an article by Jang, Seokhoon; Lee, Kyung Hyung; Lee, Jun Yeob; Lee, Youngu. COA of Formula: C5H6BNO2. The article was titled 《Novel hole blocking materials based on 2,6-disubstituted dibenzo[b,d]furan and dibenzo[b,d]thiophene segments for high-performance blue phosphorescent organic light-emitting diodes》. The information in the text is summarized as follows:

Novel hole blocking materials (HBMs) based on 2,6-disubstituted dibenzo[b,d]furan and dibenzo[b,d]thiophene segments, 3,3′,3”,3”’-(dibenzo[b,d]furan-2,6-diylbis(benzene-5,3,1-triyl))tetrapyridine (26DBFPTPy) and 3,3′,3”,3”’-(dibenzo[b,d]thiophene-2,6-diylbis(benzene-5,3,1-triyl))tetrapyridine (26DBTPTPy), are successfully designed and synthesized for high-performance blue phosphorescent organic light-emitting diodes (PhOLEDs) for the first time. Computational simulation is used to investigate the optimal structure, orbital distribution, and physicochem. properties of both mols. Thermal, optical, and electrochem. anal. shows that 26DBFPTPy and 26DBTPTPy possess high thermal stability, deep HOMO energy levels (-7.08 and -6.91 eV), and a high triplet energy (ET) (2.75 and 2.70 eV). Blue PhOLEDs with 26DBFPTPy or 26DBTPTPy as a hole blocking layer (HBL) exhibit a low turn-on voltage (3.0 V) and operating voltage (4.5 V) at 1000 cd m-2. In addition, the blue PhOLEDs with 26DBFPTPy or 26DBTPTPy show superior external quantum efficiencies (24.1 and 23.6%) and power efficiencies (43.9 and 42.7 lm W-1). They also show a very small efficiency roll-off of about 8.5% from 100 to 1000 cd m-2. Furthermore, they exhibit improved lifetimes compared to the similarly designed HBL with a pyridine electron transport unit and a Ph core structure. In the experimental materials used by the author, we found Pyridin-3-ylboronic acid(cas: 1692-25-7COA of Formula: C5H6BNO2)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. COA of Formula: C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Diketopyrrolopyrrole-based multifunctional ratiometric fluorescent probe and γ-glutamyltranspeptidase-triggered activatable photosensitizer for tumor therapy》 was published in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2020. These research results belong to Yang, Zhicheng; Xu, Weibo; Wang, Jian; Liu, Lingyan; Chu, Yanmeng; Wang, Yu; Hu, Yue; Yi, Tao; Hua, Jianli. Electric Literature of C6H4N2 The article mentions the following:

Photosensitizers can generate highly reactive oxygen species (ROS) by light excitation, causing cell damage and apoptosis. However, conventional photosensitizers cannot kill cancer cells selectively. In this work, we report a series of diketopyrrolopyrrole (DPP)-based photosensitizers, in which DPP-py with one pyridine group exhibits superior photodynamic killing effect on tumor cells. Furthermore, by introducing 4-bromomethyl-Ph glutamic acid in DPP-py, we adopt a strategy involving the intramol. charge transfer effect to develop a multifunctional DPP-based ratiometric fluorescent probe and activatable photosensitizer DPP-GGT, which can target the tumor-related biomarker γ-glutamyltranspeptidase (γ-GT). DPP-GGT shows highly selective and obvious fluorescent changes from red to yellow for γ-GT. More importantly, DPP-GGT exhibits specific photodynamic killing effects on human hepatic cancer cells HepG2 due to the high activity of endogenous γ-GT but no marked phototoxicity toward low-γ-GT-expressing breast cancer cells MCF-7 or normal hepatocyte cells L02. The results demonstrate that DPP-GGT has great potential for the tumor-specific activatable photodynamic anticancer therapy. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanopyridine(cas: 100-48-1Electric Literature of C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Electric Literature of C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Emissions from a triphenylamine-benzothiadiazole-monocarbaborane triad and its applications as a fluorescent chemosensor and a white OLED component》 were Peng, Zhixing; Zhang, Kang; Huang, Zongwei; Wang, Zaibin; Duttwyler, Simon; Wang, Yanguang; Lu, Ping. And the article was published in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2019. Recommanded Product: 4-Ethynylpyridine The author mentioned the following in the article:

A fluorescent D-A-D’ triad (1), composed of monocarbaborane, benzothiadiazole and triphenylamine, was synthesized. By replacing monocarbaborane with Ph, p-methoxyphenyl (PMP), or 4-pyridinyl (Py), 3 analogs were prepared for comparison. Monocarbaborane is an electron donating group based on the comparative anal. of NMR spectra and the systematic study of their photophys. properties. Triad 1 emits bright-yellow light in THF solution with the highest quantum yield and the longest decay time among these compounds It tends to form nanoparticles in aqueous THF solution The in situ generated nanoparticles might be used to detect Ag ions with high sensitivity and high selectivity. By holding the mols. via multiple CH···π interactions and electrostatic forces between the Et4N+ cation and the cage, a sheet-like arrangement of 1 is formed in the solid state with the smallest crystal d. that provides the maximum possibility of mechanofluorochromism from the crystalline to the ground form. By doping 1 in PVK, a white OLED is obtained. Crystallog. data are given. In the experimental materials used by the author, we found 4-Ethynylpyridine(cas: 2510-22-7Recommanded Product: 4-Ethynylpyridine)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: 4-Ethynylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Improved antifouling and self-cleaning ability of PVDF ultrafiltration membrane grafted with polymer brushes for oily water treatment》 was written by Pourziad, Sakineh; Omidkhah, Mohammad Reza; Abdollahi, Mahdi. Synthetic Route of C12H12N2 And the article was included in Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) in 2020. The article conveys some information:

This study focuses on the modification of com. polyvinylidene fluoride (PVDF) membranes using surface-initiated atom transfer radical polymerization (SI-ATRP) method. Poly(N-isopropylacrylamide) (PNIPAAm) was grafted from PVDF surface and then PEGMA was grafted onto the PVDF-g-PNIPAAm membrane. The aim of the research was to prepare membranes that simultaneously have antifouling and self-cleaning properties. PNIPAAm (lower block) was grafted to give the membrane temperature sensitive property and PPEGMA (upper block) was used to improve hydrophilicity. Morphol., topog. and chem. composition of the modified membranes were completely characterized. Antifouling and cleaning ability of modified membranes were investigated using synthetic oily water. Moreover, the role of PEGMA polymerization time on the membrane performance was examined PNIPAAm-b-PPEGMA modified membrane achieved 64% decrease in fouling ratio compared to unmodified PVDF membrane at best condition. The flux recovery was 99.1% for modified membrane at this condition. Furthermore, the unmodified PVDF membrane showed 91.1% oil rejection; while the modified membrane could reject 98.2% oil mols. The final flux of all modified membranes were higher than unmodified membrane. These results indicated that PNIPAAm-b-PPEGMA modified membranes have excellent fouling resistance and self-cleaning ability. In the part of experimental materials, we found many familiar compounds, such as 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Synthetic Route of C12H12N2)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.Synthetic Route of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《A new mononuclear zinc(II) complex: Crystal structure, DNA- and BSA-binding, and molecular modeling; in vitro cytotoxicity of the Zn(II) complex and its nanocomplex》 was written by Daryanavard, Marzieh; Jannesari, Zahra; Javeri, Mandana; Abyar, Fatemeh. Recommanded Product: 4,4′-Dimethyl-2,2′-bipyridine And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. The article conveys some information:

A new mononuclear Zn(II) complex, [Zn(Me2bpy)3](PF6)2·DMF (Me2bpy = 4,4′-dimethyl-2,2′-bipyridine), has been synthesized and fully characterized. Binding studies of the Zn(II) complex with fish sperm DNA (FS-DNA) and bovine serum albumin (BSA) were investigated using cyclic voltammetry, UV-Vis and fluorescence spectroscopies. The results showed that the majority of the interaction modes between the Zn(II) complex and DNA is a combination of the electrostatic and minor groove bindings, and the microenvironment of three aromatic amino acids residues is changed due to the interaction of the Zn(II) complex with BSA. In vitro cytotoxicity studies of the Zn(II) complex and its nanocomplex against three human carcinoma cell lines (MCF-7, A-549, and HT-29) using an MTT assay indicated that the cytotoxicity of both compounds against HT-29 and MCF-7 is higher than A-549. Moreover, the results clearly demonstrated that the aqueous colloid of the Zn(II) nanocomplex is more effective than the complex solution against HT-29 and MCF-7 cells under the same exptl. conditions. The microscopic analyses of the cancer cells showed that the Zn(II) complex apparently induces the cell apoptosis. The interactions of the Zn(II) complex with DNA and BSA were also modeled using mol. docking. The results are in good agreement with the exptl. findings. In the experiment, the researchers used many compounds, for example, 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Recommanded Product: 4,4′-Dimethyl-2,2′-bipyridine)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.Recommanded Product: 4,4′-Dimethyl-2,2′-bipyridine Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Fan, Weibin;Zhang, Yuan;Li, Yinghua;Zhang, Wei;Huang, Deguang published 《Solvent-Free Strategy for Direct Access to Versatile Quaternary Ammonium Salts with Complete Atom Economy》 in 2022. The article was appeared in 《ChemSusChem》. They have made some progress in their research.Quality Control of 3-Cyanopyridine The article mentions the following:

A solvent-free method for the synthesis of quaternary ammonium salts (QAS) such as 1-(2-Iodo-1-phenylethyl)-4-pyridinium triiodide I [R¹ = Ph, 4-MeC₆H₄, 2-ClC₆H₄, etc.; R² = H, 4-OMe, 4-C(O)OMe, etc.; X = H, N; Y = H, N] by iodoquaternization of alkenes with N-heteroarenes was reported. Its advantages lied in energy-saving and clean production by using iodine as the oxidant and manual grinding the starting materials, together with the complete atom economy and low process mass intensity (PMI) value. Generated QAS converted to pyrroles such as II [R¹ = Ph, 4-MeC₆H₄, 2-ClC₆H₄, etc.; R² = 5-SMe, C(O)Ome, C(O)Ph, etc.]. Demonstrated by 50 examples, the generated QAS was proved to be able to produce valuable chems., such as biol. protease inhibitors, anti-cancer agents, and organic fluorescent materials. And 3-Cyanopyridine (cas: 100-54-9) was used in the research process.

3-Cyanopyridine(cas: 100-54-9) has been shown to have a number of pharmacological effects: it inhibits the production of prostaglandin E2 and nitric oxide in congestive heart failure patients; it prevents the formation of diazonium salt from benzene and nitrogen dioxide; it inhibits the growth of tumor cell lines; and it protects mice from radiation injury by scavenging reactive oxygen species. Quality Control of 3-Cyanopyridine

Reference:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Category: pyridine-derivatives《Energetically significant nitrile···nitrile and unconventional C-H···π(nitrile) interactions in pyridine based Ni(II) and Zn(II) coordination compounds: Antiproliferative evaluation and theoretical studies》 was published in 2021. The authors were Das, Amal;Sharma, Pranay;Frontera, Antonio;Verma, Akalesh K.;Barcelo-Oliver, Miquel;Hussain, Sahid;Bhattacharyya, Manjit K., and the article was included in《Journal of Molecular Structure》. The author mentioned the following in the article:

Two new coordination compounds viz. [Ni(2,6-PDC)(Hdmpz)(H₂O)₂]•H₂O (1) and [Zn(3-CNpy)₂Cl₂] (2) (2,6-PDC = 2,6-pyridinedicarboxylate, Hdmpz = 3,5-dimethylpyrazole, 3-CNpy = 3-cyanopyridine) were synthesized and characterized using elemental anal., TGA, electronic, IR spectroscopy and single crystal x-ray diffraction techniques. Crystal structure analyses reveal supramol. assemblies involving interesting dimers with unconventional contacts in the compounds DFT (D. Functional Theory) calculations on the supramol. dimers in the crystal structure of 1 reveal that the sum of contributions of anion-π, π-π and other long range interactions due to the approximation of the bulk monomers is energetically significant. Mol. Electrostatic Potential (MEP) surface and Quantum Theory of Atoms in Mols. (QTAIM) analyses on the interesting supramol. dimers of the crystal structures of 2 reveal unconventional anion···π contacts involving coordinated chlorido ligands and C-H···π(nitrile) interactions involving the π-system of the nitrile moiety of 3-cyanopyridine. Remarkably, Atoms in Mols. anal. also confirms the existence of energetically significant unconventional anti-parallel nitrile···nitrile interaction in the crystal structure of 2. Cell cytotoxicity of the compounds performed in Da’s lymphoma (DL) malignant cancer cell line showed effective potency with negligible cytotoxicity in normal cells (∼12%). Compound 1 has excellent cytotoxic potency with IC₅₀ closer to cisplatin and can bind different biol. targets with similar signaling pathways. Structure activity relation (SAR) analyses of 1 and 2 based on pharmacophore modeling reveal that the mol. features associated with the structures of the compounds play important role in the biol. activities. The experimental procedure involved many compounds, such as 3-Cyanopyridine (cas: 100-54-9) .

3-Cyanopyridine(cas: 100-54-9) is an antimicrobial agent that can be used in the treatment of infectious diseases.Category: pyridine-derivatives It has been shown to be effective against a variety of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae.

Reference:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Category: pyridine-derivativesIn 2022, Zheng, Shixin;Wang, Dong;Huang, Mindong;Yu, Peng published 《Rapid Generation of Tetrahydropyridines and Tetrahydroquinolines by Dearomative Cyanation/Grignard Addition》. 《Chemistry – An Asian Journal》published the findings. The article contains the following contents:

A rapid, practical and scalable method for the reductant and tansition-metal-free synthesis of a variety of novel 2,4-disubstituted tetrahydropyridines and tetrahydroquinolines was disclosed. The method was based upon dearomative functionalization of pyridines or quinolines to generate amino nitrile intermediates as masked iminium ions, which then react rapidly with various Grignard reagents in complete stereocontrol. To complete the study, the researchers used 3-Cyanopyridine (cas: 100-54-9) .

3-Cyanopyridine(cas: 100-54-9) has been shown to have a number of pharmacological effects: it inhibits the production of prostaglandin E2 and nitric oxide in congestive heart failure patients; it prevents the formation of diazonium salt from benzene and nitrogen dioxide; it inhibits the growth of tumor cell lines; and it protects mice from radiation injury by scavenging reactive oxygen species. Category: pyridine-derivatives

Reference:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem