Tag: 600-700

The author of 《Switching between Copper-Catalysis and Photocatalysis for Tunable Halofluoroalkylation and Hydrofluoroalkylation of 1,6-Enynes toward 1-Indenones》 were Shen, Zheng-Jia; Wang, Shi-Chao; Hao, Wen-Juan; Yang, Shi-Zhao; Tu, Shu-Jiang; Jiang, Bo. And the article was published in Advanced Synthesis & Catalysis in 2019. Safety of fac-Tris(2-phenylpyridine)iridium The author mentioned the following in the article:

Radical cyclization/fluoroalkylation of enyne I with BrCF2CO2Et in presence of K2CO3 in MeCN at 120° under air using CuI and Me4Phen as catalyst afforded (E)-indenone II (68%) whereas the same substrates under visible light photocatalytic conditions with fac-Ir(ppy)3 in presence of Et3N in THF under N2 at room temperature afforded (Z)-III (59%). In the part of experimental materials, we found many familiar compounds, such as fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Safety of fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Safety of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of fac-Tris(2-phenylpyridine)iridiumIn 2019 ,《Photoredox-catalyzed cascade annulation of N-propargylindoles with sulfonyl chlorides: access to 2-sulfonated 9H-pyrrolo[1,2-a]indoles》 appeared in Organic & Biomolecular Chemistry. The author of the article were Zhang, Pengbo; Shi, Shanshan; Gao, Xia; Han, Shuang; Lin, Jinming; Zhao, Yufen. The article conveys some information:

A photoredox-catalyzed cascade radical reaction of N-propargylindoles I (R1 = H, 6-Me, 7-Me, 5-MeO, 6-F, 6-Cl, 5-Cl; R2 = H, CN, CF3, Me, MeO, F, Cl, Br, I; R3 = H, Me) and sulfonyl chlorides ArS(O)2Cl (Ar = 4-methylphenyl, naphthalen-1-yl, thiophen-2-yl, etc.) to 2-sulfonated 9H-pyrrolo[1,2-a]indoles II (R4 = 7-MeO, 7-Cl, 9-Me, etc.) was described. By the direct use of com. available sulfonyl chlorides as radical precursors, this transformation proceeded smoothly to afford the corresponding products in moderate to good yields under external oxidant-free conditions at room temperature In the experimental materials used by the author, we found fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Reference of fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Reference of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Safety of fac-Tris(2-phenylpyridine)iridiumIn 2020 ,《Multiscale Simulation of Photoluminescence Quenching in Phosphorescent OLED Materials》 was published in Advanced Theory and Simulations. The article was written by Symalla, Franz; Heidrich, Shahriar; Friederich, Pascal; Strunk, Timo; Neumann, Tobias; Minami, Daiki; Jeong, Daun; Wenzel, Wolfgang. The article contains the following contents:

Bimol. exciton-quenching processes such as triplet-triplet annihilation (TTA) and triplet-polaron quenching play a central role in phosphorescent organic light-emitting diode (PhOLED) device performance and are, therefore, an essential component in computational models. However, the experiments necessary to determine microscopic parameters underlying such processes are complex and the interpretation of their results is not straightforward. Here, a multiscale simulation protocol to treat TTA is presented, in which microscopic parameters are computed with ab initio electronic structure methods. With this protocol, virtual photoluminescence experiments are performed on a prototypical PhOLED emission material consisting of 93 wt% of 4,4′,4″”-tris(N-carbazolyl)triphenylamine and 7 wt% of the green phosphorescent dye fac-tris(2-phenylpyridine)iridium. A phenomenol. TTA quenching rate of 8.5 × 10-12 cm3 s-1, independent of illumination intensity, is obtained. This value is comparable to exptl. results in the low-intensity limit but differs from exptl. rates at higher intensities. This discrepancy is attributed to the difficulties in accounting for fast bimol. quenching during exciton generation in the interpretation of exptl. data. This protocol may aid in the exptl. determination of TTA rates, as well as provide an order-of-magnitude estimate for device models containing materials for which no exptl. data are available. In the experimental materials used by the author, we found fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Safety of fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Safety of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Visible-Light-Induced Radical Di- and Trifluoromethylation of β, γ-Unsaturated Oximes: Synthesis of Di- and Trifluoromethylated Isoxazolines》 was written by Zhu, Mei; Fun, Weijun; Guo, Wenbo; Tian, Yunfei; Wang, Zhiqiang; Xu, Chen; Ji, Baoming. Synthetic Route of C33H24IrN3This research focused ontrifluoromethylated isoxazoline preparation unsaturated oxime trifluoromethylation difluoromethylation. The article conveys some information:

The visible-light-promoted difluoromethylation and trifluoromethylation/cyclization of β, γ-unsaturated oximes was successfully accomplished with fluorinated sulfones as the difluoromethylation and trifluoromethylation reagents. The reaction is proposed to proceed through a sequence comprising CF2X-radical generation, fluoromethyl radical addition, single electron oxidation, and intramol. cyclization to afford the corresponding di and trifluoromethylated isoxazoline derivatives in an overall redox-neutral process. In the part of experimental materials, we found many familiar compounds, such as fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Synthetic Route of C33H24IrN3)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Synthetic Route of C33H24IrN3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hattori, Shingo; Hirata, Shuntaro; Shinozaki, Kazuteru published their research in Journal of Physical Chemistry B in 2021. The article was titled 《Emission Intensity Enhancement for Iridium(III) Complex in Dimethyl Sulfoxide under Photoirradiation》.COA of Formula: C33H24IrN3 The article contains the following contents:

We found emission intensity enhancement for fac-Ir(ppy)3 (ppy = 2-(2′-phenyl)pyridine) in aerated DMSO during photoirradiation for the first time. This phenomenon was concluded to be responsible for the consumption of 3O2 dissolved in DMSO through di-Me sulfone production by photosensitized reaction using fac-Ir(ppy)3. A 3O2 adduct of DMSO mol. was detected by UV absorption measurement and theor. calculation We proposed a mechanism for the emission enhancement reaction including 1,3O2 mols. and 1,3O2-DMSO adducts and validated it through a simulation of emission intensity change using an ordinary differential equation solver. The experimental part of the paper was very detailed, including the reaction process of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6COA of Formula: C33H24IrN3)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. COA of Formula: C33H24IrN3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Grafting Modification of Poly(vinylidene fluoride-trifluoroethylene) via Visible-Light Mediated C-F Bond Activation》 was written by Wang, Miao; Lei, Mingxin; Tan, Shaobo; Zhang, Zhicheng. Safety of fac-Tris(2-phenylpyridine)iridiumThis research focused onvinylidene fluoride trifluoroethylene copolymer graft polymerization bond activation. The article conveys some information:

In this work, a strategy of C-F bond activation for grafting modification of poly(vinylidene fluoride-trifluoroethylene) (h-P(VDF-TrFE), TrFE is dominantly as -CF2CH2-CFHCF2- sequence) using an Ir-based photoredox catalyst is reported. The graft polymerization exhibits first-order kinetics, and the chem. composition of the graft copolymer can be easily adjusted by changing the reaction conditions. Importantly, the side reaction of dehydrofluorination (β-H elimination) can be effectively avoided, which occurs in the previously reported copper complex catalytic system. Moreover, the purification process is greatly simplified due to the extremely low content of catalyst added. This work may provide a facile strategy for incorporating functional groups into h-P(VDF-TrFE) via directly activating C-F bond under mild conditions. In the experimental materials used by the author, we found fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Safety of fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Safety of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Angewandte Chemie, International Edition included an article by Bao, Xu; Wang, Qian; Zhu, Jieping. Product Details of 94928-86-6. The article was titled 《Dual Photoredox/Copper Catalysis for the Remote C(sp3)-H Functionalization of Alcohols and Alkyl Halides by N-Alkoxypyridinium Salts》. The information in the text is summarized as follows:

Under mild dual photoredox/copper catalysis, the reaction of N-alkoxypyridinium salts with readily available silyl reagents (TMSN3, TMSCN, TMSNCS) afforded δ-azido, δ-cyano, and δ-thiocyanato alcs. HOCH(R)(CH2)2C(R1)(R2)(R3) [R = H, Me, Et; R1 = n-Bu, Ph, (CH2)2OBn, etc.; R2 = H, Me; R1R2 = (CH2)4, (CH2)5; R3 = N3, CN, SCN] in high yields. The reaction proceeded through a domino process involving alkoxy radical generation, 1,5-hydrogen atom transfer (1,5-HAT) and copper-catalyzed functionalization of the resulting C-centered radical. Conditions for catalytic enantioselective δ-C(sp3)-H cyanation were also documented. In the experiment, the researchers used fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Product Details of 94928-86-6)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Product Details of 94928-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Direct access to 2-difluoromethyl indoles via photoredox catalysis》 were Rubinski, Miles A.; Lopez, Simon E.; Dolbier, William R. Jr.. And the article was published in Journal of Fluorine Chemistry in 2019. Reference of fac-Tris(2-phenylpyridine)iridium The author mentioned the following in the article:

A visible-light mediated approach to radical difluoromethylation of 3- and 3,5-substituted indoles was investigated using a readily synthesized difluoromethyl source, CF2HPPh3Br. Direct difluoromethylation of indoles in the two position is a rare feat in the literature. The reactions were conducted at room temperature, using Ir(ppy)3 as photocatalyst in acetone, afforded the 2-difluoromethyl indoles in relatively low to moderate yields. The experimental part of the paper was very detailed, including the reaction process of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Reference of fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Reference of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of fac-Tris(2-phenylpyridine)iridiumIn 2020 ,《Photocatalytic Isomerization of Styrenyl Halides: Stereodivergent Synthesis of Functionalized Alkenes》 was published in European Journal of Organic Chemistry. The article was written by Zhang, Hao; Xu, Qing; Yu, Lei; Yu, Shouyun. The article contains the following contents:

An efficient and general method for the isomerization of styrenyl halides under different photocatalytic conditions (fac-Ir(ppy)3 in methanol for E to Z isomerization and fluorescein in 1,4-dioxane for Z to E isomerization, resp.) was disclosed. A series of stereospecific transformations constitute preliminary validation of this strategy in the synthesis of functionalized alkenes, including two diaryl alkenes, a styrenyl boronic ester and an enyne. The photocatalytic isomerization and subsequent cross coupling reaction can be run in a one-pot manner. The stereodivergent synthesis of all four isomers of a conjugated diene, as well as the antitumor agent DMU-212 and its (Z)-isomer highlights the synthetic applicability of this method. In the experiment, the researchers used many compounds, for example, fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Reference of fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Reference of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Journal of the American Chemical Society included an article by Zhu, Min; Zheng, Chao; Zhang, Xiao; You, Shu-Li. SDS of cas: 94928-86-6. The article was titled 《Synthesis of Cyclobutane-Fused Angular Tetracyclic Spiroindolines via Visible-Light-Promoted Intramolecular Dearomatization of Indole Derivatives》. The information in the text is summarized as follows:

An intramol. dearomatization of indole derivatives based on visible-light-promoted [2+2] cycloaddition was achieved via energy transfer mechanism. The highly strained cyclobutane-fused angular tetracyclic spiroindolines, which were typically unattainable under thermal conditions, could be directly accessed in high yields (up to 99%) with excellent diastereoselectivity (> 20:1 dr) under mild conditions. The method was also compatible with diverse functional groups and amenable to flexible transformations. In addition, DFT calculations provided guidance on the rational design of substrates and deep understanding of the reaction pathways. This process constituted a rare example of indole functionalization by exploiting visible-light-induced reactivity at the excited states. The results came from multiple reactions, including the reaction of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6SDS of cas: 94928-86-6)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. SDS of cas: 94928-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem