Tag: M.W=150-200

An article Practical Method for Reductive Deuteration of Ketones with Magnesium and D2O WOS:000513082700046 published article about SELECTIVE REDUCTION; LABELED COMPOUNDS; HYDROGEN ISOTOPE; PRIMARY ALCOHOLS; DEUTERIUM; ACTIVATION; TRITIATION; DISCOVERY; SYSTEM; MILD in [Zhu, Nengbo; Su, Min; Wan, Wen-Ming; Li, Yajun; Bao, Hongli] Chinese Acad Sci, Ctr Excellence Mol Synth, Fujian Inst Res Struct Matter, State Key Lab Struct Chem,Key Lab Coal Ethylene G, Fuzhou 350002, Peoples R China in 2020.0, Cited 59.0. Category: pyridine-derivatives. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

alpha-Deuterated alcohols have important applications in pharmaceuticals and mechanism studies. Here, we report a new and practical strategy for the reductive deuteration of ketones using a Mg/BrCH2CH2Br/D2O system, which affords alpha-deuterated alcohols in good yields and with almost quantitative incorporation of deuterium. The synthetic value of this method has been demonstrated by the easy access to deuterated drugs or drug derivatives. This method may inspire the discovery of other deuterium-containing drugs.

Category: pyridine-derivatives. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Zhu, NB; Su, M; Wan, WM; Li, YJ; Bao, HL or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Towards blue emitting monocyclometalated gold(iii) complexes – synthesis, characterization and photophysical investigations WOS:000472454100034 published article about CYCLOMETALATED ALKYNYLGOLD(III) COMPLEXES; RAY CRYSTAL-STRUCTURE; LIVED EXCITED-STATES; IRIDIUM COMPLEXES; ORGANOGOLD(III) COMPLEXES; EXCITATION-ENERGIES; GOLD COMPLEXES; DEVICES; EFFICIENCY; EMISSION in [Bachmann, Michael; Fessler, Reto; Blacque, Olivier; Venkatesan, Koushik] Univ Zurich, Dept Chem, Winterthurerstr 190, CH-8057 Zurich, Switzerland; [Venkatesan, Koushik] Macquarie Univ, Dept Mol Sci, Sydney, NSW 2109, Australia in 2019.0, Cited 78.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Recommanded Product: Phenyl(pyridin-2-yl)methanone

Blue emitting phosphorescent materials with high efficiency and high stability are a key requirement for the wider adoption of organic light emitting devices (OLEDs). In order to achieve triplet derived emission at the higher energy region of the electromagnetic spectrum, a series of neutral, monocyclometalated gold(iii) complexes with trifluoromethyl and trifluoromethoxy functionalized 2-phenylpyridine (ppy) derivatives, 2-anilinopyridine (apy), 2-benzoylpyridine (bpy) and 2-benzylpyridine (bepy), as the cyclometalating framework and diaryl or monoaryl alkyne as ancillary ligands have been designed and synthesized. Extensive photophysical and chemical characterization by various nuclear magnetic resonance spectroscopy techniques, elemental analysis and single crystal X-ray diffraction studies of selected compounds was carried out to confirm the structural and the chemical identity of the complexes. The emission wavelength maxima of the complexes appear in the blue/sky blue region of the electromagnetic spectrum. Detailed photophysical investigations revealed that the different emission properties of the complexes are predominantly dictated by the electronic properties of the cyclometalating ligand. The interesting photoluminescence properties along with the facile synthetic access makes this a promising concept to obtain highly suitable blue emitting gold(iii) complexes.

Recommanded Product: Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Bachmann, M; Fessler, R; Blacque, O; Venkatesan, K or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Safety of Phenyl(pyridin-2-yl)methanone. Palav, A; Misal, B; Ganwir, P; Badani, P; Chaturbhuj, G in [Palav, Amey; Misal, Balu; Ganwir, Prerna; Chaturbhuj, Ganesh] Inst Chem Technol, Mumbai 400019, Maharashtra, India; [Palav, Amey; Misal, Balu] Loba Chem Pvt Ltd, Res & Dev Ctr, Tarapur 401506, Thane, India; [Badani, Purav] Univ Mumbai, Dept Chem, Mumbai 400098, Maharashtra, India published Rapid, chemoselective and mild oxidation protocol for alcohols and ethers with recyclable N-chloro-N-(phenylsulfonyl)benzenesulfonamide in 2021, Cited 42. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Chlorine is the 20th most abundant element on the earth compared to bromine, iodine, and fluorine, a sulfonimide reagent, N-chloro-N-(phenylsulfonyl)benzenesulfonamide (NCBSI) was identified as a mild and selective oxidant. Without activation, the reagent was proved to oxidize primary and secondary alcohols as well as their symmetrical and mixed ethers to corresponding aldehydes and ketones. With recoverable PS-TEMPO catalyst, selective oxidation over chlorination of primary and secondary alcohols and their ethers with electron-donating substituents was achieved. The reagent precursor of NCBSI was recovered quantitatively and can be reused for synthesizing NCBSI. (C) 2021 Elsevier Ltd. All rights reserved.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Palav, A; Misal, B; Ganwir, P; Badani, P; Chaturbhuj, G or concate me.. Safety of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article A highly selective ESIPT-based fluorescent probe with a large Stokes shift for the turn-on detection of cysteine and its application in living cells WOS:000447816700007 published article about AGGREGATION-INDUCED EMISSION; POLYMERIC NANOPARTICLES; ORGANIC NANOPARTICLES; LIQUID-CHROMATOGRAPHY; HYDROGEN-SULFIDE; CLICK REACTION; HUMAN PLASMA; AIE; HOMOCYSTEINE; THIOLS in [Sheng, Huace; Hu, Yonghong; Zhao, Xinxin; Yang, Wenge] Nanjing Tech Univ, Sch Pharmaceut Sci, 30 South Puzhu Rd, Nanjing 211816, Jiangsu, Peoples R China; [Hu, Yonghong; Fan, Shimin] Nanjing Tech Univ, Synerget Innovat Ctr Adv Mat, 30 South Puzhu Rd, Nanjing 211816, Jiangsu, Peoples R China; [Zhou, Yi] Nanjing Tech Univ, Coll Chem & Mol Engn, Nanjing 211816, Jiangsu, Peoples R China; [Cao, Yang] Jiangsu Prov Hosp, Nanjing 210000, Jiangsu, Peoples R China in 2019.0, Cited 58.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Recommanded Product: 91-02-1

A new imidazo [1,5-alpha]pyridine-based fluorescent probe, named MZC-AC, is developed for the detection of cysteine (Cys) based on an excited state intramolecular proton transfer (ESIPT) mechanism. The probe MZC-AC uses an acrylate moiety as the ESIPT blocking group as well as the recognition site. Upon the treatment with Cys, MZC-AC exhibits a dramatic fluorescence enhancement (85-fold) and a large Stokes shift (166 nm). The limit of detection obtained from fluorescent titration was as low as 0.07 mu M. MZC-AC displays highly sensitive and selective response to Cys over homocysteine (Hcy) and glutathione (GSH). Significantly, MZC-AC could be used to detect Cys in living cells.

Recommanded Product: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Sheng, HC; Hu, YH; Zhou, Y; Fan, SM; Cao, Y; Zhao, XX; Yang, WG or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Copper or Silver-Mediated Oxidative C(sp(2))-H/N-H Cross-Coupling of Phthalimide and Heterocyclic Arenes: Access to N-Arylphthalimides WOS:000490659000017 published article about C-H AMINATION; CATALYZED DIRECT AMIDATION; BOND-FORMATION; INTERMOLECULAR AMINATION; PALLADIUM; FUNCTIONALIZATION; COBALT; CARBON; AZOLES; NICKEL in [Gryaznova, Tatyana, V; Kholin, Kirill, V; Nikanshina, Elizaveta O.; Khrizanforova, Vera V.; Strekalova, Sofia O.; Fayzullin, Robert R.; Budnikova, Yulia H.] Russian Acad Sci, FRC Kazan Sci Ctr, Arbuzov Inst Organ & Phys Chem, Arbuzov Str 8, Kazan 420088, Russia in 2019.0, Cited 95.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. SDS of cas: 91-02-1

Copper or silver-catalyzed direct C(sp(2))-H/N-H electrochemical cross-coupling of phthalimide and heterocyclic arenes (2-phenylpyridine, benzo[h]quinoline, benzoxazole, and benzothiazole, etc.) for the efficient synthesis of phthalimide derivatives is described. This reaction features good yield, mild conditions, and broad substrate scope, which provides an efficient and straightforward protocol to access this type of tertiary amines. For the first time, the proposed protocol is based not only on a copper catalyst but also on silver, which has never been used for this purpose before, and both give comparable results. Mechanistic investigations (voltammetry, ESR studies) disclosed that a free-radical pathway might be excluded in this process accomplished through Cu(I)/Cu(II)/Cu(III) or Ag(I)/Ag(III) cycles.

SDS of cas: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Gryaznova, TV; Kholin, KV; Nikanshina, EO; Khrizanforova, VV; Strekalova, SO; Fayzullin, RR; Budnikova, YH or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: Phenyl(pyridin-2-yl)methanone. Ma, XY; Wang, P; Liu, ZH; Xin, CH; Wang, SY; Jia, JG; Ma, PT; Niu, JY; Wang, JP in [Ma, Xinyi; Wang, Ping; Liu, Zhihao; Xin, Changhui; Wang, Siyu; Jia, Jiage; Ma, Pengtao; Niu, Jingyang; Wang, Jingping] Henan Univ, Henan Key Lab Polyoxometalate Chem, Coll Chem & Chem Engn, Kaifeng 475004, Henan, Peoples R China published Oxyfunctionalization of Alkanes Based on a Tricobalt(II)-Substituted Dawson-Type Rhenium Carbonyl Derivative as Catalyst in 2020.0, Cited 61.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

POM-supported metal carbonyl derivatives (PMCDs) represent a family of tremendous potential catalysts owing to their peculiar physical and chemical properties. Yet low-valence transition metal-substituted Dawson-type PMCD catalysts are uncommon. Hence, we synthesized a tricobalt-substituted PMCDs by conventional aqueous solution method, [Na(H2O)(5)](NH4)(7)[P2W15O56Co3(H2O)(3)(OH)(3)Re(CO)(3)]center dot 13H(2)O (1), and characterized by single crystal X-ray diffraction crystallography, IR, and thermogravimetric analyses (TGA), etc. The obtained compound 1 was employed as a catalyst for the oxidation of diphenylmethane (DPM) to benzophenone, giving 96.8% yield in the presence of tert-butyl hydroperoxide (TBHP) and pyridine. The control experiments indicate that Co metal ion plays an important role in the catalytic reactions. As a side note, the electrospray ionization mass spectrometry (ESI-MS) and UV spectroscopy showed that 1 can retain its integrity in solution, and magnetic measurements indicated that 1 exhibited a weaker ferromagnetic interaction at low temperature.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Ma, XY; Wang, P; Liu, ZH; Xin, CH; Wang, SY; Jia, JG; Ma, PT; Niu, JY; Wang, JP or concate me.. Recommanded Product: Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about IODINE OXIDATION; METHYLARENES; HYDROXYPHTHALIMIDE; ESTERIFICATION; BENZALDEHYDES; HETEROCYCLE; INHIBITORS; CATALYSIS; ESTERS, Saw an article supported by the NFSCNational Natural Science Foundation of China (NSFC) [21871070, 21573064]; Fundamental Research Funds for the Central Universities (Hunan University)Fundamental Research Funds for the Central Universities. SDS of cas: 91-02-1. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Ye, RZ; Cao, YJ; Xi, XX; Liu, L; Chen, TQ. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

A metal-free and radical-free synthesis of heteroaromatic aldehydes was developed through aerobic oxidation of methyl groups in an I2/DMSO/O2 catalytic system. Under the reaction conditions, various functional groups such as methoxy, aldehyde, ester, nitro, amide, and halo (F, Cl, Br) groups were well tolerated. The bioactive compounds like chlorchinaldin derivative and papaverine were also oxidized to the corresponding aldehydes and ketones. This reaction provided an efficient method for preparing the valuable heteroaromatic aldehydes.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Ye, RZ; Cao, YJ; Xi, XX; Liu, L; Chen, TQ or concate me.. SDS of cas: 91-02-1

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Enamullah, M; Hossain, MA; Bindu, MM; Islam, MK; Zaman, MA in TAYLOR & FRANCIS LTD published article about TETRAHEDRAL ZINC(II) COMPLEXES; SCHIFF-BASE LIGANDS; CIRCULAR-DICHROISM; CRYSTAL-STRUCTURE; X-RAY; ELECTRONIC-PROPERTIES; COPPER(II) COMPLEXES; CYCLIC VOLTAMMETRY; HELICITY INVERSION; THERMAL ANALYSES in [Enamullah, Mohammed; Hossain, Mohammad Anwar; Bindu, Mortuza Mamun; Islam, Mohammad Khairul; Zaman, Mohammad Al-Moktadir] Jahangirnagar Univ, Dept Chem, Dhaka, Bangladesh in 2020.0, Cited 41.0. Computed Properties of C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

The enantiopure Schiff bases (RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamine (R-1= H and OCH3) are synthesized from reaction between the 2-benzoyl-pyridine andchiral-amine (RorS)-1-(p-R-1-C6H4)ethylamine, respectively. These Schiff bases react with the copper(II) acetate to give distorted-tetrahedralbis[(RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamino-kappa N-2,N]-Delta/?-Cu(PF6)(2)in the presence of NH4PF6. A conformational change fromcis- totrans-isomer occurs in solution and thereby, the copper(II) coordinates to the solelytrans-form to provide the complexes. Cyclic voltammograms demonstrate two quasi-reversible one electron charge transfer processes for the Cu2+/Cu(+)and Cu+/Cu(0)couples in acetonitrile. ECD spectra reveal expected mirror-image relationships and indicate enantiopurity or enantiomeric excess of theRorS-ligands and their associated complexes in solution. Comparisons of experimental and simulated ECD spectra suggest induced chirality at-metal center, which diastereoselectively provides the Delta-Cu-Ror ?-Cu-Sdiastereomer as major product in solution. DFT/TDDFT optimized structures and excited state properties correspond well to the experimental results.

Computed Properties of C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Enamullah, M; Hossain, MA; Bindu, MM; Islam, MK; Zaman, MA or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Simultaneous enrichment and analysis of tobacco alkaloids by microextraction coupled with mass spectrometry using a poly (N-isopropyl-acrylamide-co-divinyl-benzene-co-N, N ‘-methylene diacrylamide) monolithic column WOS:000462803400017 published article about SOLID-PHASE MICROEXTRACTION; SIMULTANEOUS QUANTIFICATION; NICOTINE METABOLITES; EXTRACTION; COTININE; URINE; NITROSAMINES; CAPILLARY; HAIR; EXPOSURE in [Wu, Fangling; Ding, Chuan-Fan] Ningbo Univ, Sch Mat Sci & Chem Engn, Inst Mass Spectrometry, Ningbo 315211, Zhejiang, Peoples R China; [Wu, Fangling; Yang, Shutong; Wang, Liang; Wei, Wanghui; Ding, Chuan-Fan] Fudan Univ, Dept Chem, Shanghai 200438, Peoples R China in 2019, Cited 40. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6. HPLC of Formula: C8H9NO2

Herein, we realized the simultaneous online detection of six tobacco alkaloids (TM) by in-tube solid-phase microextraction (In-tube SPME) coupled with mass spectrometry by a rapid, sensitive, and matrix effect-free method requiring no chromatographic separation and only minimal sample pre-treatment. A poly (N-isopropylacrylamide-co-divinylbenzene-co-N, N’-methylenediacrylamide) [Poly (NIPAAm-co-DVB-co-MBAA)] monolithic column was designed according to the chemical structures of selected TM and used as an extraction medium engaging in hydrophobic, pi-pi, and hydrogen bonding interactions with analytes, allowing them to be effectively extracted. A number of important parameters were systematically optimized to achieve maximal extraction efficiency. The ion intensity of the TM signals obtained by in-tube SPME-MS were higher than the direct MS mode by about 400 folds with the signal-to-noise ratio improved by 2-7 folds. The detection limits of the six TM were determined as 1.99-4.06 ng g(-1), with good linearity with correlation coefficients exceeding 0.99 obtained under optimal extraction conditions. Besides, TA recoveries in cigarette tobacco spiked at three concentration levels were in the range of 76.4-100.2%, and the corresponding RSDs (n = 5) were obtained as 4.32-7.16%. The extraction performance of the poly (NIPAAm-co-DVB-co-MBAA) monolithic column was well reproducible, with intra- or inter-day precision RSDs determined not to exceed 7.38%. Finally, no marked matrix effects were observed when the developed method was applied to the analysis of both high-abundance and trace level TM in practical samples, and the above technique was therefore concluded to be well suited for the detection of TAs in cigarette tobacco or other products.

HPLC of Formula: C8H9NO2. About Ethyl nicotinate, If you have any questions, you can contact Wu, FL; Yang, ST; Wang, L; Wei, WH; Ding, CF or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. Recently I am researching about METAL-COMPLEXES; 2-BENZOYLPYRIDINE; LIGAND; TRANSFORMATION, Saw an article supported by the Special Account of NCSR Demokritos [10813]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Danelli, P; Tsantis, ST; Kitos, A; Psycharis, V; Raptopoulou, CP; Tsipis, A; Perlepes, SP. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Two diastereoisomers of bis(2-benzoylpyridine-O,N)dichloridonickel(II) have been isolated from the reactions of nickel(II) chloride hexahydrate and the organic ligand depending on the reaction solvent (ethanol, acetonitrile) used. DFT studies indicate that one of the isomers is more stable in both solvents, but nevertheless different diastereoisomers are crystallized from the two solvents. The two complexes represent the first pair of well characterized diastereoisomers in the coordination chemistry of 2-pyridyl ketones, providing a new example in the chemistry of octahedral MA(2)(BC) over cap (2) complexes (A = a monodentate ligand, (BC) over cap = an unsymmetrical bidentate chelate).

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Danelli, P; Tsantis, ST; Kitos, A; Psycharis, V; Raptopoulou, CP; Tsipis, A; Perlepes, SP or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem