Tag: M.W=300-350

Williams, Jack L. R. published the artcilePhotochemical decomposition of triphenylboron and its complexes, HPLC of Formula: 971-66-4, the publication is Journal of the American Chemical Society (1967), 89(17), 4538, database is CAplus.

In the direct photolysis of triphenylboron (I) in solution and N atm. by 2537 A. radiation, the formation of hydrocarbon products depended on the nature of the solvent. With I in cyclohexane, the products were only phenol and phenylboronic acid. When I was irradiated in MeOH solution, biphenyl and diene mixtures of products were obtained in low yields. Under similar conditions in MeOH solution, the piperidine complex of I yielded 32% biphenyl, 26% 1-phenyl-1,3-cyclohexadiene, 23% 1-phenyl-1,4-cyclohexadiene, and a small amount of 2-phenyl-1,3-cyclohexadiene. Similarly, the pyridine complex of I gave 63% biphenyl, 10% 1-phenyl-1,4-cyclohexadiene, 7% 3-phenyl-1,4-cyclohexadiene, and 4% 1-phenyl-1,3-cyclohexadiene. Since the absorption maximum of I depended also on the nature of the solvent, it was concluded that the alc. mol. donated an electron pair to the B atom to promote the “ate”-type photochem. rearrangement.

Journal of the American Chemical Society published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C17H16O2, HPLC of Formula: 971-66-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Oliveira, Isabel B. published the artcileToxicity of emerging antifouling biocides to non-target freshwater organisms from three trophic levels, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate, the publication is Aquatic Toxicology (2017), 164-174, database is CAplus and MEDLINE.

Antifouling (AF) systems provide the most cost-effective protection against biofouling. Several AF biocides have, however, caused deleterious effects in the environment. Subsequently, new compounds have emerged that claim to be more environment-friendly, but studies on their toxicity and environmental risk are necessary in order to ensure safety. This work aimed to assess the toxicity of three emerging AF biocides, tralopyril, triphenylborane pyridine (TPBP) and capsaicin, towards non-target freshwater organisms representing three trophic levels: algae (Chlamydomonas reinhardtii), crustacean (Daphnia magna) and fish (Danio rerio). From the three tested biocides, tralopyril had the strongest inhibitory effect on C. reinhardtii growth, effective quantum yield and ATP (ATP) content. TPBP caused sub-lethal effects at high concentrations (100 and 250μg L^-1), and capsaicin had no significant effects on algae. In the D. magna acute immobilization test, the most toxic compound was TPBP. However, tralopyril has a short half-life and quickly degrades in water. With exposure solution renewals, tralopyril’s toxicity was similar to TPBP. Capsaicin did not cause any effects on daphnids. In the zebrafish embryo toxicity test (zFET) the most toxic compound was tralopyril with a 120 h – LC₅₀ of 5μg L^-1. TPBP’s 120 h – LC₅₀ was 447.5μg L^-1. Capsaicin did not cause mortality in zebrafish up to 1 mg L^-1. Sub-lethal effects on the proteome of zebrafish embryos were analyzed for tralopyril and TPBP. Both general stress-related and compound-specific protein changes were observed Five proteins involved in energy metabolism, eye structure and cell differentiation were commonly regulated by both compounds Tralopyril specifically induced the upregulation of 6 proteins implicated in energy metabolism, cytoskeleton, cell division and mRNA splicing while TPBP lead to the upregulation of 3 proteins involved in cytoskeleton, cell growth and protein folding. An ecol. risk characterization was performed for a hypothetical freshwater marina. This anal. identified capsaicin as an environment-friendly compound while tralopyril and TPBP seem to pose a risk to freshwater ecosystems. Noneless, more studies on the characterization of the toxicity, behavior and fate of these AF biocides in the environment are necessary since this information directly affects the outcome of the risk assessment.

Aquatic Toxicology published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zahn, Helmut published the artcileA derivative of O-(2,4-dinitrophenyl)-DL-serine, Computed Properties of 971-66-4, the publication is Biochemische Zeitschrift (1955), 209-12, database is CAplus.

The N content of carefully purified cotton after exhaustive treatment with 2,4-(O₂N)₂C₆H₃F (Ia) (cf. C.A. 46, 7144i) increases from 0.09 to 0.22% indicating that the hydroxyl in serine has not reacted. α-N-Benzoylamino-β-hydroxyethyl propionate (I) (1.5 g.) and 1.1 g. Ia in 30 ml. dry C₆H₆, refluxed 6 hrs., evaporated in vacuo, and the residue treated with 15 ml. 2N HCl gave 5% EtCO₂CH(NHBz)CH₂OC₆H₃(NO₂)₂-2,4 (II), m. 122° (from EtOH). I (0.7 g.) was treated with 1.5 g. PhN:NC₆H₄COCl-p in 30 ml. C₅H₅N, and after 2 days H₂O added and the mass evaporated in vacuo. The residue dissolved in 50 ml. CHCl₃, extracted with aqueous KHSO₄, and chromatographed on Al₂O₃ yielded EtCO₂CH(NHBz)CH₂O₂CC₆H₄N:NPh-p, m. 154°.

Biochemische Zeitschrift published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is 0, Computed Properties of 971-66-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Hohmann, Urszula published the artcileNimodipine Exerts Time-Dependent Neuroprotective Effect after Excitotoxical Damage in Organotypic Slice Cultures, Computed Properties of 21829-25-4, the publication is International Journal of Molecular Sciences (2022), 23(6), 3331, database is CAplus and MEDLINE.

During injuries in the central nervous system, intrinsic protective processes become activated. However, cellular reactions, especially those of glia cells, are frequently unsatisfactory, and further exogenous protective mechanisms are necessary. Nimodipine, a lipophilic L-type calcium channel blocking agent is clin. used in the treatment of aneurysmal subarachnoid hemorrhage with neuroprotective effects in different models. Direct effects of nimodipine on neurons amongst others were observed in the hippocampus as well as its influence on both microglia and astrocytes. Earlier studies proposed that nimodipine protective actions occur not only via calcium channel-mediated vasodilatation but also via further time-dependent mechanisms. In this study, the effect of nimodipine application was investigated in different time frames on neuronal damage in excitotoxically lesioned organotypic hippocampal slice cultures. Nimodipine, but not nifedipine if pre-incubated for 4 h or co-applied with NMDA, was protective, indicating time dependency. Since blood vessels play no significant role in our model, intrinsic brain cell-dependent mechanisms seems to strongly be involved. We also examined the effect of nimodipine and nifedipine on microglia survival. Nimodipine seem to be a promising agent to reduce secondary damage and reduce excitotoxic damage.

International Journal of Molecular Sciences published new progress about 21829-25-4. 21829-25-4 belongs to pyridine-derivatives, auxiliary class Membrane Transporter/Ion Channel,Calcium Channel, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C17H18N2O6, Computed Properties of 21829-25-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Scott, Georgia published the artcileGuidelines-similarities and dissimilarities: a systematic review of international clinical practice guidelines for pregnancy hypertension, Name: Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, the publication is American Journal of Obstetrics and Gynecology (2022), 226(2_Suppl.), S1222-S1236, database is CAplus and MEDLINE.

A review. This study aimed to review pregnancy hypertension clin. practice guidelines to inform international clin. practice and research priorities. Relevant national and international clin. practice guidelines, 2009-19, published in English, French, Dutch or German. Following published methods and prospective registration (CRD42019123787), a literature search was updated. CPGs were identified by 2 authors independently who scored quality and usefulness for practice (Appraisal of Guidelines for Research and Evaluation II instrument), abstracted data, and resolved any disagreement by consensus. Of note, 15 of 17 identified clin. practice guidelines (4 international) were deemed “clin. useful” and had recommendations abstracted. The highest Appraisal of Guidelines for Research and Evaluation II scores were from government organizations, and scores have improved over time. The following were consistently recommended: (1) automated blood pressure measurement with devices validated for pregnancy and preeclampsia, reflecting increasing recognition of the prevalence of white-coat hypertension and the potential usefulness of home blood pressure monitoring; (2) use of dipstick proteinuria testing for screening followed by quant. testing by urinary protein-to-creatinine ratio or 24-h urine collection; (3) key definitions and most aspects of classification, including a broad definition of preeclampsia (which includes proteinuria and maternal end-organ dysfunction, including headache and visual symptoms and laboratory abnormalities of platelets, creatinine, or liver enzymes) and a recognition that it can worsen after delivery; (4) preeclampsia prevention with aspirin; (5) treatment of severe hypertension, most commonly with i.v. labetalol, oral nifedipine, or i.v. hydralazine; (6) treatment for nonsevere hypertension when undertaken, with oral labetalol (in particular), methyldopa, or nifedipine, with recommendations against the use of renin-angiotensin-aldosterone inhibitors; (7) magnesium sulfate for eclampsia treatment and prevention among women with “severe” preeclampsia; (8) antenatal corticosteroids for preterm birth but not hemolysis, elevated liver enzymes, and low platelet count syndrome; (9) delivery at term for preeclampsia; (10) a focus on usual labor and delivery care but avoidance of ergometrine; and (11) an apprecia. Lack of uniformity was seen in the following areas: (1) the components of a broad preeclampsia definition (specifically respiratory and gastrointestinal symptoms, fetal manifestations, and biomarkers), what constitutes severe preeclampsia, and whether the definition has utility because at present what constitutes severe preeclampsia by some guidelines that mandate proteinuria now defines any preeclampsia for most other clin. practice guidelines; (2) how preeclampsia risk should be identified early in pregnancy, and aspirin administered for preeclampsia prevention, because multivariable models (with biomarkers and ultrasonog. added to clin. risk markers) used in this way to guide aspirin therapy can substantially reduce the incidence of preterm preeclampsia; (3) the value of calcium added to aspirin for preeclampsia prevention, particularly for women with low intake and at increased risk of preeclampsia; (4) emerging recommendations to normalize blood pressure with antihypertensive agents even in the absence of comorbidities; (5) fetal neuroprotection as an indication for magnesium sulfate in the absence of “severe” preeclampsia; and (6) timing of birth for chronic and gestational hypertension and preterm preeclampsia. Consistent recommendations should be implemented and audited. Inconsistencies should be the focus of research.

American Journal of Obstetrics and Gynecology published new progress about 21829-25-4. 21829-25-4 belongs to pyridine-derivatives, auxiliary class Membrane Transporter/Ion Channel,Calcium Channel, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C13H18BBrO3, Name: Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kaewchuay, Netnapit published the artcileSimultaneous determination of pyridine-triphenylborane anti-fouling agent and its degradation products in paint-waste samples using capillary zone electrophoresis with field-amplified sample injection, COA of Formula: C23H20BN, the publication is Analytical Sciences (2012), 28(12), 1191-1196, database is CAplus and MEDLINE.

We proposed a capillary zone electrophoresis (CZE) procedure using field-amplified sample injection (FASI) for the simultaneous determination of pyridine-triphenylborane (PTPB) and its degradation products: diphenylborinic acid (DPB), phenylboronic acid (MPB), and phenol. The LODs for PTPB, DPB, MPB, and phenol were, resp., 0.85, 0.88, 44, and 28 μg/L. The RSDs (n =4) for the analytes listed above were 6.2-14, 5.9-10, and 0.49-0.62% for the peak area, peak height, and migration time, resp. The compounds were extracted from paint-waste samples collected from shipyards using a silica-gel column. The extract was dissolved with acetonitrile containing 1% (volume/volume) pyridine. The samples were then analyzed using CZE, revealing resp. concentrations of 0.076-0.53, 0.015-0.36, 1.7-22, and 1.2-13 μg/g. The proposed FASI-CZE method is a simple and promising procedure that is expected to be useful for the determination of PTPB and its degradation products in paint wastes.

Analytical Sciences published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, COA of Formula: C23H20BN.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Yakushiji, Yuki published the artcileEvaluation for degradation of pyridine-triphenylborane anti-fouling agent in acetonitrile using capillary zone electrophoresis, Computed Properties of 971-66-4, the publication is Bunseki Kagaku (2009), 58(4), 301-304, database is CAplus.

A com. organoborane compound, pyridine-triphenylborane (PTPB), is often applied to ship hulls as an anti-fouling agent in order to keep them free from marine organisms, such as barnacles and bivalves. However, the degradation process of PTPB and its degradation products have not been well understood, because of lack of an anal. method for both PTPB and its estimated degradation products. We previously developed a procedure using capillary zone electrophoresis (CZE) with direct UV detection for the simultaneous determination of PTPB and its estimated degradation products, such as diphenylborinic acid (DPB), phenylboronic acid (MPB), and phenol. For this study, simple degradation experiments were carried out to verify the usefulness of the proposed method for further PTPB degradation investigations. That is to say, PTPB samples dissolved in acetonitrile were put in the open air and a dark place to examine the effects of the light intensity and the temperature on the degradation of PTPB. The sample solutions were analyzed by the CZE method with the elapse of time. As a result, it was suggested that the degradation of PTPB was significantly affected by the light intensity, rather than the temperature It has consequently been demonstrated that the CZE method is a useful tool to elucidate the degradation process of PTPB and its degradation products.

Bunseki Kagaku published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C6H5F4NO3S, Computed Properties of 971-66-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kitamura, Akira published the artcileApplication of KU 5SDH-2 pelletron accelerator to elemental analyses of marine-environmental substances and agricultural products, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate, the publication is Kobe Daigaku Daigakuin Kaiji Kagaku Kenkyuka Kiyo (2007), 147-154, database is CAplus.

Two subjects offered in reply to a campaign for promotion of accelerator application are studied. One is quant. anal. of B content in the seabed mud, which might be related to triphenylboranepyridine (TPBP) currently used as antifouling agent. Nuclear reaction anal. (NRA) using ¹¹B(p,3α) reaction is able to quantify B concentration of the order of ppm in highly pure C, and the seabed mud in Fukae port contains B with a concentration of the order of 100 ppm, which is one order of magnitude greater than that in the earth crust. The other is elemental anal. of garlic to distinguish the place of its cultivation. Particle-induced-x-ray-emission (PIXE) anal. and ⁷Li(p,2α)-NRA are successfully applied to find that the garlic cultivated in China contains richer amount of Fe, Sr and Li than domestic one by a factor of 3.0, 2.4 and 94, resp. The accelerator analyses could be widely applied in a variety of fields of environmental science and agriculture.

Kobe Daigaku Daigakuin Kaiji Kagaku Kenkyuka Kiyo published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Pan, Huaqiang published the artcileInfluencing factors and evaluation of CaCO₃ modified with three coupling agents, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate, the publication is Wuhan Keji Daxue Xuebao (2013), 36(1), 64-68, database is CAplus.

KH101, KH151 and KH570 were used to modify the surface of CaCO₃, resp., to improve the surface properties, and the optimum modification conditions were determined by analyzing the factors that influenced the activation grade of modified CaCO₃. The modification effects of three coupling agents were compared by means of SEM anal. and settling volume test. The results show that, the optimum conditions for KH101 modification of CaCO₃ are the reaction temperature at 80°C, the reaction time at 70 min, the coupling agent content at 3%, and the amount of cyclohexanone five times that of CaCO₃, and the optimum conditions for KH570 and KH151 modification of CaCO₃ are the reaction temperature at 70°C, the reaction time at 70 min, the coupling agent content at 3%, and the amount of cyclohexanone five times that of CaCO₃. It is also found that modification with KH151 and KH570 is characterized by severe reunion phenomenon, while modification with KH101 can remarkably ameliorate the reunion phenomenon of CaCO₃.

Wuhan Keji Daxue Xuebao published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Spring Walsh, Breeanna published the artcileA Cohort Comparison Study on Women in Threatened Preterm Labor Given Nifedipine or Nifedipine and Salbutamol Tocolysis in Air Medical Retrieval., HPLC of Formula: 21829-25-4, the publication is Air medical journal (2022), 41(3), 298-302, database is MEDLINE.

OBJECTIVE: Women with threatened preterm labor in remote Australia often require tocolysis in the prevention of in-flight birth during air medical retrieval. However, debate exists over the tocolytic choice. METHODS: A retrospective analysis was undertaken on data containing women who required air medical retrieval for threatened preterm labor within Western Australia between the years 2013 and 2018. RESULTS: A total number of 236 air medical retrievals were deemed suitable for inclusion; 141 received nifedipine, and 95 women received salbutamol + nifedipine. Tocolytic efficaciousness was reported in 151 cases, proportionally more (P < .05) from the women who received salbutamol + nifedipine (n = 68, 71.6%) compared with the women who received nifedipine only (n = 83, 58.9%). Those receiving salbutamol + nifedipine were more likely to suffer maternal tachycardia (n = 87 [91.6%] vs. n = 62 [44.0%]), fetal tachycardia (n = 26 [27.4%] vs. n = 13 [9.2%]), nausea (n = 17 [17.9] vs. n = 5 [3.55%]), and vomiting (n = 12 [12.6%] vs. n = 2 [1.4%]). Three women who received salbutamol + nifedipine had serious side effects including echocardiographic changes, chest pain, and metabolic and lactic acidosis. CONCLUSION: Salbutamol + nifedipine tocolysis was proven to be more effective than nifedipine only. Although salbutamol + nifedipine had increased temporary side effects, most were nonsevere and managed in-flight.

Air medical journal published new progress about 21829-25-4. 21829-25-4 belongs to pyridine-derivatives, auxiliary class Membrane Transporter/Ion Channel,Calcium Channel, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C9H5FO2, HPLC of Formula: 21829-25-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem