Tag: M.W=300-400

Shirani, Farzaneh; Mazdak, Ali; Mazaheri, Peiman; Shirani, Mehrangiz; Samimi, Pouran published the artcile< Evaluation of the effect of anti-COVID-19 mouthwashes on shear bond strength of composite resin restorations to dentin and enamel: an ""in vitro study"">, Name: 1-Hexadecylpyridin-1-ium chloride, the main research area is dentin enamel shear bond strength mouthwash coronavirus disease 2019.

Given the high prevalence of the coronavirus and the high risk of virus transfer to dentists, the use of mouthwashes, which can potentially eliminate this virus, is suggested before dental procedures. Since these mouthwashes may affect the bond strength of composite resin restorations to teeth, this study was conducted to investigate the effect of recommended mouthwashes on the shear bond strength of composite resin restorations to dentin and enamel in selective etch and rinse and two-step self-etch bonding systems. Five groups of posterior teeth (n = 15) were selected for five groups of cetylpyridinium chloride 0.07%, povidone-iodine 1%, hydrogen peroxide 1%, and chlorhexidine 0.2% as mouthwash and distilled water as the control group. The buccal enamel and lingual dentin of each tooth were rinsed after immersion in a mouthwash. After 20 s of enamel acid-etching and 15 s of dentin priming, they were impregnated with an adhesive, and composite cylinders were placed on the dentin and enamel surfaces of the tooth. The shear bond strength test was performed after 24 h, and results were analyzed by ANOVA and paired t-test (α = 0.05). The mean shear bond strength of enamel to composite was significantly (p = 0.05) higher than that of dentin to composite in each study group, but no significant difference was found between the mean shear bond strength of composite to enamel (p = 0.199) and to dentin (p = 0.335) after the use of mouthwashes and that of the control group. The use of mouthwashes used in this study did not have neg. effects on the shear bond strength of composite to enamel and dentin.

BioMed Research International published new progress about Bond energy (shear). 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Name: 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Guo, Wenjing; Fu, Zhiyou; Zhang, Zhiyong; Wang, Hao; Liu, Shasha; Feng, Weiying; Zhao, Xiaoli; Giesy, John P. published the artcile< Synthesis of Fe3O4 magnetic nanoparticles coated with cationic surfactants and applications in Sb(V) removal from water>, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride, the main research area is synthesis Fe3O4 magnetic nanoparticle coated cationic surfactant Sb removal; Adsorption; Fe(3)O(4); Magnetic nanoparticle; Sb(V); Surfactant.

Antimony (Sb) pollution was an emerging environmental risk in several contaminated waters, whereas its removal still presented as a severe challenge due to the lack of efficient adsorbent and its further removal mechanism. In this study, synthesized absorbents, Fe3O4 magnetic nanoparticles (Fe-MNPs) modified and dispersed with commonly used cationic surfactants, were applied to remove Sb contamination in real surface waters, its synthesized conditions, removal performance and mechanism were investigated by using batch experiments and characterization analyses. Optimum conditions on Sb(V) (the dominant form is Sb(OH)-6) removal by modified adsorbents were obtained as: cetylpyridinium chloride (CPC) coated on Fe-MNPs, mass ratio of Fe-MNPs: CPC = 4:1 and pH = 3-5. Magnetic properties of synthesized adsorbent were not affected, dispersibility was enhanced after fabrication of CPC, that indicated the Fe-MNPs@CPC could be separated and reused with external magnetic field. The adsorption efficiency of this low-cost adsorbent coated with CPC was superior than several traditional adsorbents. The practical application of Fe-MNPs@CPC in five types real waters from the Xikuangshan (XKS) Sb mine area and regeneration experiments by 1 M (mol/L) NaOH solution further confirm its practicability and reusability. Removal experiment results, XPS and Fourier transform IR spectroscopy (FT-IR) spectra suggested that electrostatic attraction and surface bonding might responsible for the Sb(V) removal by Fe-MNPs modified with cationic surfactants.

Science of the Total Environment published new progress about Adsorbents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Fizer, Oksana; Fizer, Maksym; Sidey, Vasyl; Studenyak, Yaroslav published the artcile< Predicting the end point potential break values: A case of potentiometric titration of lipophilic anions with cetylpyridinium chloride>, Category: pyridine-derivatives, the main research area is Predicting end point potential break values potentiometric titration.

The applicability of cetylpyridinium chloride for potentiometric titration of lipophilic anions has been studied. The specially developed cetylpyridinium-selective plasticized electrode has been used for the investigation of the mechanism of interaction between the cetylpyridinium cation and lipophilic anions, which obviously goes through the association reaction resulting in the formation of water-insoluble precipitates The investigated 54 anions were placed in the selectivity row that strongly correlates with lipophilicity. Addnl., an attempt has been made to find a simple and reliable descriptor suitable for prediction of the value of the end point potential break and thus indicating the applicability of the described potentiometric method for determination of untested lipophilic anions of interest. It has been established that despite being well known lipophilicity estimators, molar weight, octanol-water distribution coefficient logP, logarithm of solubility logS, and hydrophilicity-lipophilicity index can not be sep. used for directly predicting the end point potential break values. However, simultaneous anal. of the above descriptors by using the multiple linear regression technique has resulted in the development of a reasonable QSPR model for the estimation of the potential break values near the end point.

Microchemical Journal published new progress about Chemical potential. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Munoz-Basagoiti, J.; Perez-Zsolt, D.; Leon, R.; Blanc, V.; Raich-Regue, D.; Cano-Sarabia, M.; Trinite, B.; Pradenas, E.; Blanco, J.; Gispert, J.; Clotet, B.; Izquierdo-Useros, N. published the artcile< Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro>, Formula: C21H38ClN, the main research area is cetylpyridinium chloride mouthwash virucide COVID19; COVID-19; airborne transmission; cellular infection; coronaviruses; oral hygiene; virucide.

Oral mouthwashes decrease the infectivity of several respiratory viruses including SARS-CoV-2. However, the precise agents with antiviral activity in these oral rinses and their exact mechanism of action remain unknown. Here we show that cetylpyridinium chloride (CPC), a quaternary ammonium compound in many oral mouthwashes, reduces SARS-CoV-2 infectivity by inhibiting the viral fusion step with target cells after disrupting the integrity of the viral envelope. We also found that CPC-containing mouth rinses decreased more than a thousand times the infectivity of SARS-CoV-2 in vitro, while the corresponding vehicles had no effect. This activity was effective for different SARS-CoV-2 variants, including the B.1.1.7 or Alpha variant originally identified in United Kingdom, and in the presence of sterilized saliva. CPC-containing mouth rinses could therefore represent a cost-effective measure to reduce SARS-CoV-2 infectivity in saliva, aiding to reduce viral transmission from infected individuals regardless of the variants they are infected with.

Journal of Dental Research published new progress about Antiviral agents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Ying; Du, Na; Song, Shue; Hou, Wanguo published the artcile< Adsorption of Cetylpyridinium Chloride at Silica Nanoparticle/Water Interfaces (I): Dependence of Adsorption Equilibrium on Particle Size>, SDS of cas: 123-03-5, the main research area is adsorption cetylpyridinium chloride silica nanoparticle size water interface equilibrium.

In the current work, a size-effect model was developed to describe the particle size-dependence of adsorption at solid/liquid interfaces. A parameter, ΔQad, was introduced, defined as the change of the product of the solid/liquid interfacial tension and the molar volume of solid surface components caused by adsorption. The model predicts that with a decrease in particle radius (r), the saturation adsorption amount per unit area (Γm, mol/m2) decreases, while the change of the adsorption equilibrium constant (Kad) is determined by the ΔQad, namely, it decreases if ΔQad > 0 but increases if ΔQad < 0. There exists a critical r at which the saturation adsorption amount per unit mass (Γmg, mol/g) attains a maximum In addition, the adsorption of cetylpyridinium chloride (CPyCl), a cationic surfactant, on silica nanoparticles with different r (ca. 6-61 nm) values was determined at 298 K and pH 9, showing an obvious size-dependence. With a decrease in r, Kad and Γm decrease, indicating a decrease in the affinity of silica particles toward CPyCl. The size-dependent adsorption data can be well described using our model. Adsorption can affect the molar volume of the solid surface phase, which plays an important role in the size-dependence of adsorption. This work provides a better understanding of the size-dependent adsorption phenomenon at solid/liquid interfaces. Langmuir published new progress about Adsorption. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, SDS of cas: 123-03-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rajendiran, Meenakshi; Trivedi, Harsh M.; Chen, Dandan; Gajendrareddy, Praveen; Chen, Lin published the artcile< Recent development of active ingredients in mouthwashes and toothpastes for periodontal diseases>, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride, the main research area is review cetylpyridinium chloride mouthwash toothpaste periodontal disease; active ingredients; gingivitis; mouthwashes; periodontal diseases; periodontitis; plaque; toothpastes.

A review. Periodontal diseases like gingivitis and periodontitis are primarily caused by dental plaque. Several antiplaque and anti-microbial agents have been successfully incorporated into toothpastes and mouthwashes to control plaque biofilms and to prevent and treat gingivitis and periodontitis. The aim of this article was to review recent developments in the antiplaque, anti-gingivitis, and anti-periodontitis properties of some common compounds in toothpastes and mouthwashes by evaluating basic and clin. studies, especially the ones published in the past five years. The common active ingredients in toothpastes and mouthwashes included in this review are chlorhexidine, cetylpyridinium chloride, sodium fluoride, stannous fluoride, stannous chloride, zinc oxide, zinc chloride, and two herbs-licorice and curcumin. We believe this comprehensive review will provide useful up-to-date information for dental care professionals and the general public regarding the major oral care products on the market that are in daily use.

Molecules published new progress about Formulation active agents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Saud, Zack; Tyrrell, Victoria J.; Zaragkoulias, Andreas; Protty, Majd B.; Statkute, Evelina; Rubina, Anzelika; Bentley, Kirsten; White, Daniel A.; Rodrigues, Patricia Dos Santos; Murphy, Robert C.; Kofeler, Harald; Griffiths, William J.; Alvarez-Jarreta, Jorge; Brown, Richard William; Newcombe, Robert G.; Heyman, James; Pritchard, Manon; Mcleod, Robert WJ.; Arya, Arvind; Lynch, Ceri-Ann; Owens, David; Jenkins, P. Vince; Buurma, Niklaas J.; O’Donnell, Valerie B.; Thomas, David W.; Stanton, Richard J. published the artcile< The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses>, Related Products of 123-03-5, the main research area is lipidome cetylpyridinium chloride oral rinse phospholipid SARSCoV2 envelope; CPC; aminophospholipids; cetylpyridinium chloride; clinical trials; coagulation; inflammation; lipidomics; mouthwash; phospholipids; virology.

The lipid envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an essential component of the virus; however, its mol. composition is undetermined Addressing this knowledge gap could support the design of antiviral agents as well as further our understanding of viral-host protein interactions, infectivity, pathogenicity, and innate immune system clearance. Lipidomics revealed that the virus envelope comprised mainly phospholipids (PLs), with little cholesterol or sphingolipids, indicating significant differences from host membranes. Unlike cellular membranes, procoagulant amino-PLs were present on the external side of the viral envelope at levels exceeding those on activated platelets. Accordingly, virions directly promoted blood coagulation. To investigate whether these differences could enable selective targeting of the viral envelope in vivo, we tested whether oral rinses containing lipid-disrupting chems. could reduce infectivity. Products containing PL-disrupting surfactants (such as cetylpyridinium chloride) met European virucidal standards in vitro; however, components that altered the critical micelle concentration reduced efficacy, and products containing essential oils, povidone-iodine, or chlorhexidine were ineffective. This result was recapitulated in vivo, where a 30-s oral rinse with cetylpyridinium chloride mouthwash eliminated live virus in the oral cavity of patients with coronavirus disease 19 for at least 1 h, whereas povidone-iodine and saline mouthwashes were ineffective. We conclude that the SARS-CoV-2 lipid envelope (i) is distinct from the host plasma membrane, which may enable design of selective antiviral approaches; (ii) contains exposed phosphatidylethanolamine and phosphatidylserine, which may influence thrombosis, pathogenicity, and inflammation; and (iii) can be selectively targeted in vivo by specific oral rinses.

Journal of Lipid Research published new progress about Antiviral agents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Related Products of 123-03-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dong, Dong; Thomas, Nicky; Ramezanpour, Mahnaz; Psaltis, Alkis J.; Huang, Shuman; Zhao, Yulin; Thierry, Benjamin; Wormald, Peter-John; Prestidge, Clive A.; Vreugde, Sarah published the artcile< Inhibition of Staphylococcus aureus and Pseudomonas aeruginosa biofilms by quatsomes in low concentrations>, Name: 1-Hexadecylpyridin-1-ium chloride, the main research area is Staphylococcus Pseudomonas biofilm quatsome; CPC-quatsome; Chronic rhinosinusitis; Pseudomonas aeruginosa; Staphylococcus aureus; biofilm; cetylpyridinium chloride.

This study investigated the inhibition effect of cetylpyridinium chloride (CPC)-quatsomes at low concentrations on both S. aureus and P. aeruginosa biofilms in vitro, as well as their toxicities towards cultured human airway epithelial (NuLi-1) cells. CPC-quatsome and CPC micelle solutions at concentrations of 0.01%, 0.025%, and 0.05% were prepared Confocal laser scanning microscopy (CLSM) was used to investigate the interactions between CPC-quatsomes and S. aureus and P. aeruginosa biofilms. A lactate dehydrogenase (LDH) assay was used to determine the toxicity of CPC-quatsomes on NuLi-1 cells. CPC-quatsome and CPC micelle solutions had significant inhibition effects at all tested concentrations on planktonic S. aureus and P. aeruginosa and their biofilms. In the CLSM study, different interactions between CPC-quatsomes and S. aureus or P. aeruginosa biofilms were observed CPC-quatsomes at low concentrations inhibited S. aureus and P. aeruginosa in both planktonic form and biofilms. No adverse effects on NuLi-1 cells were observed, indicating their promising potential in the treatment of CRS. In our study, CPC-quatsomes at concentrations of 0.01%, 0.025%, and 0.05% had significant inhibition effects on both planktonic and biofilms of S. aureus and P. aeruginosa. The result of this study indicates the promising potential of CPC-quatsome in the treatment of CRS.

Experimental Biology and Medicine (London, United Kingdom) published new progress about Biofilms (microbial). 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Name: 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nishiyama, Hisao; Yamaguchi, Shinobu; Park, Soon Bong; Itoh, Kenji published the artcile< New chiral bis(oxazolinyl)bipyridine ligand (bipymox): enantioselection in the asymmetric hydrosilylation of ketones>, Formula: C22H26N4O2, the main research area is asym hydrosilylation ketone rhodium complex catalyzed; bisoxazolinylbipyridine rhodium complex preparation catalyst hydrosilylation; stereoselective reduction ketone rhodium complex catalyzed; phenylethanol.

A homochiral chiral bis(oxazolinyl)bipyridine ligand I (bipymox) and its rhodium complex II were synthesized to examine the enantioselectivity in the asym. hydrosilylation of ketones in comparison to other chiral oxazoline ligands such as bis(oxazolinyl)pyridine III (pybox) and mono(oxazolinyl)pyridine IV (pymox). The bipymox-rhodium catalyst gave (S)-1-phenylethanol (90% enantiomeric excess) in the reduction of acetophenone with diphenylsilane, the same as the pybox-rhodium system but opposite to the pymox-rhodium system. The reduction of 4-tert-butylcyclohexanone is also described.

Tetrahedron: Asymmetry published new progress about Hydrosilylation catalysts. 147409-41-4 belongs to class pyridine-derivatives, and the molecular formula is C22H26N4O2, Formula: C22H26N4O2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xu, Jianxiong; Du, Guo; Xie, Lei; Yuan, Kai; Zhu, Yirong; Xu, Lijian; Li, Na; Wang, Xianyou published the artcile< Three-Dimensional Walnut-Like, Hierarchically Nanoporous Carbon Microspheres: One-Pot Synthesis, Activation, and Supercapacitive Performance>, Electric Literature of 123-03-5, the main research area is supercapacitor hierarchically nanoporous carbon template walnut like activation.

A one-pot synthesis of three-dimensional walnut-like, hierarchically nanoporous carbon microspheres (HNCMs) via a dual-template method was reported. In our protocol, the organic mesomorphous complexes of hexadecylpyridinium chloride/poly(acrylic acid) (CPC/PAA) were employed as a dynamic soft template; the in situ generated silica during the hydrolysis of tetraethylsiloxane (TEOS) was applied as the hard template and sucrose, as the carbon precursor. When the amount of PAA added was varied, hierarchically nanoporous carbons with other novel morphologies such as having a hexagonal nanoplate, being dumbbell-like, and having a hexagonal microprism were synthesized in a controlled manner. Besides, the pore structure of HNCMs was tailored by tuning the molar ratio of sucrose and TEOS. It was demonstrated that the specific capacitance of the HNCMs was correlated with the orderliness of the mesopores. HNCMs-15 synthesized under the molar ratio of sucrose/TEOS at 15 with well-ordered mesopores exhibited the highest specific capacitance of 232 F g-1 at 1 A g-1. The as-prepared HNCMs-15 was further chem. activated, which resulted in the activated HNCMs-15 (AHNCMs-15) with no obvious morphol. change but a high proportion of micropores, large surface area, and superior electrochem. properties (high specific capacitance of 413 F g-1 at 1 A g-1, excellent rate capability). The AHNCMs-15-based sym. supercapacitor displayed a high energy d. of 14.7 Wh kg-1 at a power d. of 250 W kg-1 and small capacitance fading (only 1.6%) after 10 000 cycles at 2 A g-1. Our strategy provides a way for the controlled synthesis of hierarchically nanoporous carbon with well-defined morphol. and structure and excellent electrochem. properties, which makes them promising electrode materials for high-performance supercapacitors. A one-pot synthesis of three-dimensional walnut-like, hierarchically nanoporous carbon microspheres for high-performance sustainable electrochem. energy device, was reported.

ACS Sustainable Chemistry & Engineering published new progress about Carbonization. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Electric Literature of 123-03-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem