Tag: M.W=350-400

Chaplin, Adrian B. published the artcile[Rh{NC₅H₃-2,6-(CH₂PtBu₂)₂}(PCy₃)][BArF₄]: A Latent Low-Coordinate Rhodium(I) PNP Pincer Compound, Application In Synthesis of 338800-13-8, the publication is Organometallics (2011), 30(16), 4466-4469, database is CAplus.

An expedient new route to the cationic [(PNP^tBu)Rh(L)]⁺ metal fragments (PNP^tBu = κ³-NC₅H₃-2,6-(CH₂P ^tBu₂)₂; L = CO, acetone, ethene, MeCN, N₂) by the synthesis of, then substitution of PCy₃ in, [(PNP^tBu)Rh(PCy₃)][BAr^F₄] is reported. This synthetic route also allows for the synthesis of the new dihydrogen complex [(PNP^tBu)Rh(H₂)][BAr^F₄]. [(PNP^R)Rh(PCy₃)][BAr^F₄] (R = Ph, Cy, Mes) are also reported, in which the PCy₃ ligand is more tightly bound to the metal center.

Organometallics published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C23H43NP2, Application In Synthesis of 338800-13-8.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Liu, Xin published the artcileSelective Construction of C-C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides, Recommanded Product: 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, the publication is Advanced Synthesis & Catalysis (2021), 363(4), 1096-1104, database is CAplus.

The manganese complex e.g., I catalyzed coupling of alcs. ROH (R = benzyl, cyclohexyl, furan-2-ylmethyl, etc.) with phosphorus ylides R¹ = P(C₆H₅)₃ (I) [R¹ = H, C(O)OEt, (morpholin-4-yl)carbonyl, benzoyl, etc.] were reported. The selectivity in the coupling of primary alcs. with phosphorus ylides (I) to form carbon-carbon single (C-C) and carbon-carbon double (C=C) bonds can be controlled by the ligands. In the conversion of more challenging secondary alcs. with phosphorus ylides (I), the selectivity towards the formation of C-C vs is obtained. C=C bonds can be controlled by the reaction conditions, namely the amount of base. The scope and limitations of the coupling reactions were thoroughly evaluated by the conversion of 21 alcs. and 15 ylides. Notably, compared to existing methods, which are based on precious metal complexes as catalysts, the present catalytic system is based on earth abundant manganese catalysts e.g., I. The reaction can also be performed in a sequential one-pot reaction generating the phosphorus ylide in situ followed manganese catalyzed C-C and C=C bond formation. Mechanistic studies suggest that the C-C bond was generated via a borrowing hydrogen pathway and the C=C bond formation followed an acceptorless dehydrogenative coupling pathway.

Advanced Synthesis & Catalysis published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C23H43NP2, Recommanded Product: 2,6-Bis((di-tert-butylphosphino)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Prechtl, Martin H. G. published the artcileDirect coupling of alcohols to form esters and amides with evolution of H₂ using in situ formed ruthenium catalysts, Recommanded Product: 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, the publication is Catalysis Science & Technology (2012), 2(10), 2039-2042, database is CAplus.

A simple approach for the catalytic conversion of primary alcs. into their corresponding esters and amides, with evolution of H₂ gas using in situ formed ruthenium PNP- and PNN-pincer catalysts (I; X = NEt₂,P-tert-Bu₂), is presented. The evaluation showed conversions for the esterification with turnover numbers as high as 4300, and >400 for the amidation.

Catalysis Science & Technology published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C23H43NP2, Recommanded Product: 2,6-Bis((di-tert-butylphosphino)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Qiao, Jun published the artcileMagnetically Reusable Fe3O4@NC@Pt Catalyst for Selective Reduction of Nitroarenes, Related Products of pyridine-derivatives, the publication is Catalysts (2021), 11(10), 1219, database is CAplus.

A novel reusable Fe3O4@NC@Pt heterogeneous catalyst was synthesized by immobilizing platinum on nitrogen-doped carbon magnetic nanostructures. It was characterized by IR anal. (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and vibrating sample magnetometer (VSM). The catalytic efficiency of Fe3O4@NC@Pt was investigated by reduction of nitro aromatic compounds The catalyst showed good catalytic activity, wide range of substrates, and good chem. selectivity, especially for the substrates of compounds containing halide and carbonyl groups. The magnetically catalyst can readily be reused up to ten cycles without loss of catalytic activity. Moreover, the key pharmaceutical intermediate Lorlatini can be facilely achieved through this strategy.

Catalysts published new progress about 1454848-00-0. 1454848-00-0 belongs to pyridine-derivatives, auxiliary class Aromatic Fluorinated Building Blocks, name is (R)-Methyl 2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate, and the molecular formula is C15H14BrFN2O3, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Nerush, Alexander published the artcileTemplate Catalysis by Metal-Ligand Cooperation. C-C Bond Formation via Conjugate Addition of Non-activated Nitriles under Mild, Base-free Conditions Catalyzed by a Manganese Pincer Complex, Category: pyridine-derivatives, the publication is Journal of the American Chemical Society (2016), 138(22), 6985-6997, database is CAplus and MEDLINE.

The first example of a catalytic Michael addition reaction of non-activated aliphatic nitriles to α,β-unsaturated carbonyl compounds under mild, neutral conditions is reported. A new de-aromatized pyridine-based PNP pincer complex of the Earth-abundant, first-row transition metal manganese serves as the catalyst. The reaction tolerates a variety of nitriles and Michael acceptors with different steric features and acceptor strengths. Mechanistic investigations including temperature-dependent NMR spectroscopy and DFT calculations reveal that the cooperative activation of alkyl nitriles, which leads to the generation of metalated nitrile nucleophile species (α-cyano carbanion analogs), is a key step of the mechanism. The metal center is not directly involved in the catalytic bond formation but rather serves, cooperatively with the ligand, as a template for the substrate activation. This approach of “template catalysis” expands the scope of potential donors for conjugate addition reactions.

Journal of the American Chemical Society published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C23H43NP2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Porter, William W. III published the artcileIsolation and Characterization of Phenyl Viologen as a Radical Cation and Neutral Molecule, HPLC of Formula: 47369-00-6, the publication is Journal of Organic Chemistry (2005), 70(13), 5028-5035, database is CAplus and MEDLINE.

The chem. synthesis, isolation, and characterization of Ph viologen (PV) as a dication, radical cation, and neutral species are described. Single-crystal X-ray diffraction of PV²⁺2Cl^–·2H₂O and PV^â€?PF₆^–·pyridine reveals the expected differences in bond lengths and also a structural change from two coplanar central rings in PV^â€? to a twist of 36° between the two central rings in PV²⁺. The Ph viologen radical cation exhibits behavior characteristic of many radical cations, including weak π-dimerization in the solid state and reversible π-dimerization in solution Elec. conductivity measurements of neutral Ph viologen, the first such measurements of a neutral viologen, reveal that it is a significantly better conductor than the radical cation. Differences in geometric relaxation during charge transfer offer a possible explanation for the higher conductivity of the neutral viologen.

Journal of Organic Chemistry published new progress about 47369-00-6. 47369-00-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Salt,Benzene,Organic ligands for MOF materials,Nitrogen containing MOF ligands,Nitrogen containing MOF ligands, name is 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride, and the molecular formula is C22H18Cl2N2, HPLC of Formula: 47369-00-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lutz, Martin published the artcileA reversible solid-solid phase transition Z’=1 to Z’=6 in [Ni(OAc)(PNP^tBu)]OTf, COA of Formula: C23H43NP2, the publication is Polyhedron (2009), 28(12), 2341-2346, database is CAplus.

At ambient temperature, [Ni(OAc)(PNP^tBu)]OTf has one independent mol. in the asym. unit of the crystal structure with very large anisotropic displacement parameters. During cooling a fully reversible solid-solid phase transition occurs at a discrete temperature in the range 210-230 K The low-temperature phase has six independent, well ordered mols. in the asym. unit. The P2₁/a space group symmetry of the high-temperature phase changes to P2₁/n for the low-temperature phase and the c-axis increases by a factor of six. The acetate ligand is coordinated in a η ¹-fashion through one of the O atoms, with the sterically encumbered, tridentate PNP^tBu ligand completing the square planar geometry around the Ni^II ion. The synthesis and full characterization of the complex is reported. Crystallog. data are given.

Polyhedron published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C23H43NP2, COA of Formula: C23H43NP2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Stambuli, James P. published the artcileScreening of Homogeneous Catalysts by Fluorescence Resonance Energy Transfer. Identification of Catalysts for Room-Temperature Heck Reactions, Computed Properties of 338800-13-8, the publication is Journal of the American Chemical Society (2001), 123(11), 2677-2678, database is CAplus and MEDLINE.

The authors report a method to screen for transition metal-catalyzed reactions based on Fluorescence Resonance Energy Transfer (FRET) and the use of this assay to identify catalysts for room-temperature Heck reactions of aryl bromides.

Journal of the American Chemical Society published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C22H23ClN4, Computed Properties of 338800-13-8.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bachurin, S. O. published the artcileRole of dopamine uptake system in the development of experimental parkinsonism induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine and its pyridine analogs, Application of 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride, the publication is Doklady Akademii Nauk SSSR (1989), 307(3), 740-3 [Biochem.], database is CAplus.

The effects of the title drug (I), an agent inducing exptl. parkinsonism, and 8 of its pyridine and dipyridyl analogs on brain content of monoamines, behavior, and synaptosomal reuptake of dopamine were studied in mice. Two daily doses of the agents at 80-90% of their LD₅₀ did not affect (except I) the brain levels of noradrenaline, dopamine, and serotonin within 5-7 days and the behavior within 3 mo. In vitro, all the agents reversibly and competitively inhibited [¹⁴C]dopamine uptake by the brain synaptosomes. The tetradehydro-I was the strongest inhibitor which is also an in vivo metabolite of I. The inhibitory effects of the other agents were partially related to their structure and lipophilicity.

Doklady Akademii Nauk SSSR published new progress about 47369-00-6. 47369-00-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Salt,Benzene,Organic ligands for MOF materials,Nitrogen containing MOF ligands,Nitrogen containing MOF ligands, name is 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride, and the molecular formula is C22H18Cl2N2, Application of 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

van der Vlugt, Jarl Ivar published the artcileA Cationic Ag^I(PNP^tBu) Species Acting as PNP Transfer Agent: Facile Synthesis of Pd(PNP^tBu)(alkyl) Complexes and Their Reactivity Compared to PCP^tBu Analogues, COA of Formula: C23H43NP2, the publication is Organometallics (2009), 28(24), 7025-7032, database is CAplus.

The straightforward synthesis of cationic complex I, [Ag(PNP^tBu)]BF₄ (PNP^tBu = 1,2-bis[(di-tert-butylphosphino)methyl]pyridine), and its facile transmetalating properties toward gold and palladium are described. The corresponding Au complex [Au(PNP^tBu)]₂(BF₄)₂ (2) exists as a dimer in the solid state, as deduced by x-ray crystallog. The transmetalating properties were expanded to include the formation of Pd-alkyl species. Reaction of I with 0.5 equiv of Pd(allyl)(μ-Cl) dimer led to clean formation of the [Pd(PNP^tBu)(η¹-allyl)]BF₄ complex 3. The analogous cationic Me (4), cyanophenyl (5), and chloro species (6) could also be prepared in good yields from appropriate Pd precursors via this transmetalation methodol. The mol. structures for complexes 3–5 were established by x-ray crystallog. Reaction of complexes 4 and 6 with NaN(SiMe₃)₂ led to deprotonation and dearomatization of the PNP backbone with formation of the neutral Pd species 7 and 8, which can be regarded as the diphosphino-monoamido N-ligated analogs of well-studied Pd(PCP^tBu) complexes. These neutral Pd(PN^–P^tBu) complexes 7 and 8 displayed reasonable activity in the Suzuki-Miyaura coupling of phenylboronic acid pinacol ester and bromoarenes.

Organometallics published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C20H40O2, COA of Formula: C23H43NP2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem