Talik, Zofia; Brekiesz-Lewandowska, Barbara published an article in 1970, the title of the article was 2-Fluoro-5-nitro-6-methylpyridine. II. Replacement of fluorine atom.Application In Synthesis of N,N-DIethyl-6-methyl-5-nitro-2-pyridinamine And the article contains the following content:
In the exchange reaction of the title compound with NH3, amines, hydrazine, water, and MeONa, I were prepared (X, m.p., and % yield given): NH2, 187°, 92.1; MeNH, 129°, 97.8; EtNH, 87°, 92.5; NHC2H4OH, 110°, 79.4; NHNH2, 122°, 74.7; PhNH, 133°, 97.2; NH(CH2)5Me, 50°, 98.5; C6H11NH, 113°, 98.5; PhNHNH, 142°, 96.5; Me2N, 132°, 86.2; Et2N, 38°, 95.4; morpholinyl, 137°, 98.2; OH, 230°, 94.1; MeO, 68°, 71.2. The experimental process involved the reaction of N,N-DIethyl-6-methyl-5-nitro-2-pyridinamine(cas: 28489-43-2).Application In Synthesis of N,N-DIethyl-6-methyl-5-nitro-2-pyridinamine
N,N-DIethyl-6-methyl-5-nitro-2-pyridinamine(cas:28489-43-2) belongs to pyridine-derivatives. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Application In Synthesis of N,N-DIethyl-6-methyl-5-nitro-2-pyridinamine