Tayama, Eiji published the artcileBase-induced Sommelet-Hauser rearrangement of N-(pyridinylmethyl) tetraalkylammonium salts, HPLC of Formula: 24484-93-3, the main research area is acylmethyl pyridylammonium bromide Sommelete Hauser rearrangement bond activation; acyl aminomethylpyridine preparation.
The base-induced Sommelet-Hauser (S-H) rearrangement of various types of N-(pyridinylmethyl) tetraalkylammonium salts to produce N,N-dialkyl-α-pyridinylamino acid esters were investigated. For example, a treatment of N-(2-pyridinylmethyl) glycine tert-Bu ester-derived tetraalkylammonium salt with 1.2 equiv of potassium tert-butoxide in THF at -40°C gave the corresponding S-H product, I [R = Obut; R1 = R2 = Me; R3= H] in 93% yield. Method was an efficient C-H functionalization of pyridines under simple and mild conditions.
Tetrahedron published new progress about Aralkyl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 24484-93-3 belongs to class pyridine-derivatives, name is Methyl 4-chloropicolinate, and the molecular formula is C7H6ClNO2, HPLC of Formula: 24484-93-3.