The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 62936-56-5, Name is Sodium 4-(nicotinamido)butanoate, SMILES is O=C([O-])CCCNC(C1=CC=CN=C1)=O.[Na+], in an article , author is Nazeri, Mohammad Taghi, once mentioned of 62936-56-5, Safety of Sodium 4-(nicotinamido)butanoate.
Chemo- and Diastereoselective Synthesis of Pyrazolo-tetrahydropyridines via Multicomponent Sequential Aza-Diels-Alder Reactions in Water
In this study, we report a novel and an efficient strategy for the synthesis of chemo- and diastereoselective synthesis of pyrazolo-tetrahydropyridines via a one-pot multi-component intramolecular Aza-Diels-Alder reactions (ADARs) from benzoylacetonitrile derivatives, phenylhydrazine, salicylaldehyde derivatives, and styrenesulfonyl or cinnamoyl chloride in H2O as a green solvent. This synthesis procedure was also designed to follow the group-assisted purification (GAP) chemistry, which can avoid traditional purification such as recrystallization and chromatography methods.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem