The important role of 1211518-35-2

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1211518-35-2, Methyl 6-chloro-5-(trifluoromethyl)picolinate.

Reference of 1211518-35-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1211518-35-2, name is Methyl 6-chloro-5-(trifluoromethyl)picolinate, molecular formula is C8H5ClF3NO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

A mixture of methyl 6-chloro-5-(trifluoromethyl)pyridine-2-carboxylate (see procedure 2, step B) (200 mg; 0.83 mmol), morpholine (73 muL; 0.83 mmol); N,N-diisopropylethylamine (159 muL; 0.92 mmol) and 3 mL of dimethyl sulfoxide is stirred for 1 hour at 120C. The reaction is quenched with methanol, filtered and purified by reverse phase chromatography-HPLC (modifier: trifluoroacetic acid). (0398) Yield: 110 mg (45 % of theory) (0399) Mass spectrometry (ESI+): m/z = 291 [M+H]+ (0400) HPLC (Method 3): Retention time = 1.021 min

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1211518-35-2, Methyl 6-chloro-5-(trifluoromethyl)picolinate.

Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; TRIESELMANN, Thomas; GODBOUT, Cedrickx; HOENKE, Christoph; VINTONYAK, Viktor; (130 pag.)WO2019/149660; (2019); A1;,
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