Electric Literature of 1211523-71-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1211523-71-5, name is 2-(2-Bromopyridin-3-yl)acetonitrile. This compound has unique chemical properties. The synthetic route is as follows.
In a three-necked flask equipped with a reflux condenser, lithium and aluminium hydride(1.95 mmol) was dissolved in anhydrous THF (2 mL). In a dropping funnel, aluminum chloride(1.95 mmol) dissolved in THF (3 mL) was added rapidly to the hydride solution. After five minutes, a solution of 2-(2-bromopyridin-3-yl) acetonitrile (1.77 mmol) in THF (4 mL) was added dropwise. One hour later, diethylether (40 mL) was added before adding a solution of 6 N sulphuric acid to reach an acidic pH. The mixture was extracted with diethylether. The pH of the aqueous layer was adjusted to 12 then extracted again with diethylether. The organic layer was dried then evaporated to afford a yellow oil (50%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1211523-71-5, 2-(2-Bromopyridin-3-yl)acetonitrile.
Reference:
Article; Balieu, Sebastien; Toutah, Krimo; Carro, Laura; Chamoreau, Lise-Marie; Rousseliere, Helene; Courillon, Christine; Tetrahedron Letters; vol. 52; 22; (2011); p. 2876 – 2880;,
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