Synthetic Route of 179687-79-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 179687-79-7, name is 2-((2-Chloro-4-nitrophenoxy)methyl)pyridine. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: A mixture of the relevant nitro derivative (1a-d) (1 equiv., 3 mmol), reduced iron powder (3 equiv., 9 mmol, 0.5 g) and NH4Cl (9 equiv., 27 mmol, 1.44 g) in 70% EtOH/H2O (20 mL) was heated at reflux temperature (70 oC) for 2 hours. The reaction mixture was filtered over a Celite pad to remove the insoluble iron oxides. The filtrate was evaporated under vacuum to residue, to which EtOAc was added, then the resulting suspension was filtered to remove the inorganic salts. The filtrate was dried over anhydrous Na2SO4 and evaporated under vacuum affording crystals of the designated compounds (2a-d), then the crystals were washed with cold n-hexane. [2-4]
According to the analysis of related databases, 179687-79-7, the application of this compound in the production field has become more and more popular.
Reference:
Article; Milik, Sandra N.; Abdel-Aziz, Amal Kamal; Lasheen, Deena S.; Serya, Rabah A.T.; Minucci, Saverio; Abouzid, Khaled A.M.; European Journal of Medicinal Chemistry; vol. 155; (2018); p. 316 – 336;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem