Adding a certain compound to certain chemical reactions, such as: 18368-59-7, 3-Bromo-4-methylpyridin-2-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 18368-59-7, blongs to pyridine-derivatives compound. Formula: C6H6BrNO
Synthesis of interaiediate V-c : 3 -Bromo-2-methoxy-4-methyl -pyridineA solution of 3-bromo-4-methyl-2-pyridone V-b (2.20 g, 11.7 mmol), in DCM (80 mL) was treated with Mel (7.29 mL, 117 mmol) and Ag2C03 (6.47 g, 23.5 mmol). The flask was stoppered and stirred under argon for 6 days. The mixture was filtered and purified by column chromatography (Si02; 10% EtOAc in cyclohexane) to afford the desired product V-c as a clear mobile oil (1.83 g, 80%). 1H NMR (300 MHz, CDC13) delta 7.94 (d, J = 5.0 Hz, 1H), 6.77 (d, J= 5.1 Hz, 1H), 4.00 (s, 3H), 2.39 (s, 3H).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,18368-59-7, its application will become more common.
Reference:
Patent; AB SCIENCE; BENJAHAD, Abdellah; MOUSSY, Alain; CHEVENIER, Emmanuel; PICOUL, Willy; LERMET, Anne; PEZ, Didier; MARTIN, Jason; SANDRINELLI, Franck; WO2013/14170; (2013); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem