Reference of 524955-09-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 524955-09-7, name is 3-Chloro-4-(pyridin-2-ylmethoxy)aniline. This compound has unique chemical properties. The synthetic route is as follows.
Compound 40 (0.66 g, 2.56 mmol), 26 (0.6 g, 2.56 mmol) and pyridine hydrochloride (0.3 g, 2.56 mmol) were added to DME (15 mL) and the solution was heated to reflux for 5 h. The reaction mixture was diluted with water (100 mL) and the resulting solid was filtered, washed with water and dried to give 4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-5-(4-nitrophenyl)nicotinonitrile 43a (0.88 g, 75%) as a faint-yellow solid. MS-ESI (m/z): 458.4(M+H), 480.3(M+Na); 1H NMR (DMSO-d6, delta): 5.19(d, 2H), 6.99-7.08(m, 2H), 7.18(s, 1H), 7.37(m, 1H), 7.47(d, 1H), 7.67(d, 2H), 7.85(t, 1H), 8.21(d, 2H), 8.34(s, 1H), 8.57(d, 1H), 8.66(s, 1H), 8.72(s, 1H).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 524955-09-7, 3-Chloro-4-(pyridin-2-ylmethoxy)aniline.
Reference:
Article; Mao, Yongjun; Zhu, Wenxiu; Kong, Xiaoguang; Wang, Zhen; Xie, Hua; Ding, Jian; Terrett, Nicholas Kenneth; Shen, Jingkang; Bioorganic and Medicinal Chemistry; vol. 21; 11; (2013); p. 3090 – 3104;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem