55758-02-6, Adding a certain compound to certain chemical reactions, such as: 55758-02-6, 3-Bromopicolinonitrile, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 55758-02-6, blongs to pyridine-derivatives compound.
Step C 2-Cyano-3-(ethylthio)pyridine To a stirred suspension of sodium ethanethiolate (600 mg, 5.75 mmol) in dry THF (25 mL) was added 3-bromo-2-cyanopyridine (700 mg, 3.83 mmol). The reaction mixture was heated to reflux under N2 for 3 h. The solvent was removed in vacuo and the resulting residue was taken Lip in CH2Cl2 (35 mL). The solution was filtered to remove precipitated sodium bromide and the filtrate was concentrated at reduced pressure to afford the title compound as a yellow oil: 1H NMR (CDCl3, 300 MHz): delta8.49 (dd, J=3.3, 1.2 Hz, 1H), 7.76 (d, J=1.2 Hz, 1H), 7.45-7.41 (m, 1H), 3.06 (q, J=7.2 Hz, 2H), 1.40-1.32 (m, 3H).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,55758-02-6, its application will become more common.
Reference:
Patent; Merck & Co., Inc.; US6387911; (2002); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem