Related Products of 6515-09-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6515-09-9, name is 2,3,6-Trichloropyridine. This compound has unique chemical properties. The synthetic route is as follows.
In a 2000-liter reactor, 546 kg of methanol, 182 kg of 2,3,6-trichloropyridine, 0.546 kg of 5% palladium-carbon (55% water), 28 kg of magnesium hydroxide and 46 kg of formic acid were added, and the mixture was stirred and heated up. At 40 degrees Celsius, nitrogen was replaced three times, and then hydrogen was introduced to maintain the pressure at 0.1-0.4 MPa. After 4 hours of reaction, the reaction was stopped to obtain a reaction solution. The reaction solution was filtered again, palladium carbon catalyst was recovered, and the first filtrate was obtained. The first filtrate was rectified and methanol was rectified for the next batch of cycle reactions. After the distillation of methanol is completed, water is added to the system to obtain a mixed and melted organic liquid of 2,3,6-trichloropyridine and 2,3-dichloropyridine.The organic liquid was slowly added dropwise to 182 kg of 25% hydrochloric acid, stirred at 5-10 degrees Celsius for 4 hours, and then pressure-filtered to recover 75 kg of unreacted 2,3,6-trichloropyridine and obtain the second filtrate. . At 10-15 degrees Celsius, 500 kg of water was added to the second filtrate to precipitate 2,3-dichloropyridine, which was filtered to give a product of 75 kg. In this embodiment, 5% palladium-carbon (water containing 55%) means that in the palladium carbon catalyst, the mass percentage of palladium is 5%, and the water content is 55%.Based on the improvement of the reaction process, the amount of palladium carbon catalyst used in the present invention is greatly reduced. The product was found to have a content of 2,3-dichloropyridine of 99% and a yield of 87%.
According to the analysis of related databases, 6515-09-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Lier Chemical Co., Ltd.; Li Yuedong; Ren Jie; Li Jianwei; Liu Qiang; He Hongyun; (6 pag.)CN107721913; (2018); A;,
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