Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 89402-42-6, name is 2,3-Difluoro-5-(trifluoromethyl)pyridine. A new synthetic method of this compound is introduced below., Product Details of 89402-42-6
Example 4 3-Fluoro-2-phenylthio-5-trifluoromethylpyridine At 148-156 C., 59.6 g (0.326 mol) of 2,3-difluoro-5-trifluoromethylpyridine were added over a period of 2.5 h to 37.7 g (0.338 mol) of 98.7% pure thiophenol and 2.1 mg (0.01 mol %) of copper powder, and the mixture was stirred at 156-164 C. for 2 hours. After cooling, the residue was taken up in methylene chloride, washed with 0.5 N aqueous sodium hydroxide solution and water, dried over magnesium sulfate and concentrated under reduced pressure. 88.9 g (100% of theory) of the title compound of
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 89402-42-6, 2,3-Difluoro-5-(trifluoromethyl)pyridine.
Reference:
Patent; BASF Aktiengesellschaft; US6191280; (2001); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem