As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 956003-24-0, name is 3-Iodo-1H-pyrrolo[2,3-c]pyridine, molecular formula is C7H5IN2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Recommanded Product: 956003-24-0
To a mixture of azaindole 1 (150 mg, 0.615 mmol) and 2-bromoethanol (115 mg, 0.923 mmol) in DMF (3 mL) is added K2C03 (170 mg, 1.23 mmol). The mixture is stirred at 40 C for 2 h then poured into water (30 mL), and extracted with EtOAc (50 mL x 3). The combined EtOAc is washed with brine, and concentrated in vacuo. The residue is purified by prep-HPLC to afford Example 25 (18 mg, yield= 6 %).
With the rapid development of chemical substances, we look forward to future research findings about 956003-24-0.
Reference:
Patent; DISARM THERAPEUTICS, INC.; HUGHES, Robert Owen; DEVRAJ, Rajesh; BOSANAC, Todd; JARJES-PIKE, Richard Andrew; BREARLEY, Andrew Simon; BENTLEY, Jonathan; (0 pag.)WO2019/236884; (2019); A1;,
Pyridine – Wikipedia,
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