Reference of 55279-30-6, Adding some certain compound to certain chemical reactions, such as: 55279-30-6, name is Methyl 3-aminoisonicotinate,molecular formula is C7H8N2O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 55279-30-6.
4. Preparation of Methyl 3-Amino-2-chloroisonicotinate A mixture of 18 g (118 mmol) of methyl 3-aminoisonicotinate and 12 g (60 mmol) of 1,3-dichloro-5,5-dimethylhydantoin in 1500 mL of tetrachloroethylene was warmed slowly to 80 C. with stirring and held there for 3 hours. The solution was then cooled, filtered, washed with dilute aqueous sodium bicarbonate, dried over magnesium sulfate, filtered, and concentrated by evaporation under reduced pressure to obtain a dark oil. This oil was purified by careful column chromatography to give 6.7 g (30 percent of theory) of the title compound as a colorless solid melting at 91-92 C. Elemental Analysis C7 H7 ClN2 O2 Calc.: %C, 45.1; %H, 3.78; %N, 15.0 Found: %C, 45.2; %H, 3.94; %N, 15.1 1 H NMR CDCl3: 7.7 (d, 1H, J=5.1); 7.6 (d, 1H, J=5.1); 6.2 (br, 2H); 3.9 (s, 3H); 13 C NMR CDCl3: 166.7, 141.9, 139.0, 134.7, 122.8, 116.5, 52.3.
According to the analysis of related databases, 55279-30-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; DowElanco; US5461161; (1995); A;,
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