Application of 17282-40-5, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.17282-40-5, name is 1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium bromide, molecular formula is C9H12BrNO2, molecular weight is 246.1011, as common compound, the synthetic route is as follows.
General procedure: To a magnetically stirred solution of N- functionalized pyridinium, isoquinolinum, or quinolinium salt 1, 4, or 5 (1 mmol) and triphenylphosphine (1 mmol) in 3 mL DMF was added solution of alkyl propiolate 2 (1 mmol) in 2 mL DMF at -5-0 C temperature. The reaction mixture stirred for 12 h, and then the mixture was poured onto H2O (5 mL), extracted with AcOEt (15 mL), dried (MgSO4), and the solvent was removed under reduced pressure. The residue was separated by silica gel (Merck 230-240 mesh) column chromatography using hexane-ethyl acetate mixture as eluent.
Statistics shows that 17282-40-5 is playing an increasingly important role. we look forward to future research findings about 1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium bromide.
Reference:
Article; Hashemi, Seyed Abolghasem; Khalili, Gholamhossein; Synthetic Communications; vol. 45; 21; (2015); p. 2491 – 2497;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem